In CHF, depression is observed 2-3 times more often than in other diseases, currently this value ranges from 13% to 77% of the sample of patients with CHF. According to foreign and domestic research, these figures are much higher in the hospital. The average age of patients with CHF is quite old, which naturally aggravates the emotional background and the ability to withstand stress. On the other hand, this is also a general trend associated with an increase in the number of cases of depression worldwide. Among the depressions in cardiac diseases, in particular, in CHF, two leading types can be distinguished: nosogenic depression, associated with the peculiarities of the individual's response to the disease, and somatogenic depression (a disorder caused by the disease itself). The effect of the antidepressant paroxetine was studied in 89 elderly patients with chronic heart failure III FC according to NYHA and signs of anxiety-depressive personality disorder. The results of the study indicate the high clinical efficacy of rexetin: positive changes in the mental status of patients, their somatic state and quality of life have been established

chronic heart failure, senile age, anxiety and depressive disorders, paroxetine.

Khabibovna, Y. S., Alisherovna, K. M., Nizamitdinovich, K. S., & Totlibayevich, Y. S. (2023). Features of heart failure in patients with thyrotoxicosis. Journal of new century innovations, 29(1), 89-97.

Khabibovna, Y. S., Alisherovna, K. M., Tashtemirovna, E. M. M., Totlibayevich, Y. S., Nizamitdinovich, K. S., & Baxtiyorovich, U. J. (2023). DIAGNOSTIC VALUE OF CYSTATIN C IN PATIENTS WITH HYPERTENSION AND OBESITY. World Bulletin of Public Health, 22, 55-59.

Khabibovna, Y. S., Alisherovna, K. M., Nizamitdinovich, K. S., Tashtemirovna, E. M. M., Abdukadirovna, A. S., & Jasurovna, J. S. (2023). DEPRESSION, ANXIETY AND QUALITY OF LIFE IN PATIENTS WITH ATRIAL FIBRILLATION. Journal of new century innovations, 39(1), 185-189.

Khabibovna, Y. S., Alisherovna, K. M., Tashtemirovna, E. M. M., & Baxtiyorovich, U. J. (2023). THE EFFECTIVENESS OF THYROSTATICS IN THE TREATMENT OF. Journal of new century innovations, 29(1), 79-88.

Khabibovna, Y. S., & Alisherovna, K. M. (2024). STRESS TESTING IN PATIENTS WITH CORONARY HEART DISEASE. Journal of new century innovations, 45(3), 28-33.

Khabibovna, Y. S., & Xudoyberdiyevich, G. X. (2024). THE POSSIBILITIES OF COENZYME Q10 AS PART OF THE COMPLEX THERAPY OF PATIENTS WITH CHRONIC HEART FAILURE. Spectrum Journal of Innovation, Reforms and Development, 25, 116-123.

Tashtemirovna, E. M. M., Khabibovna, Y. S., Alisherovna, K. M., & Erkinovna, K. Z. (2023). Angiopathy in Rheumatoid Arthritis. Miasto Przyszłości, 40, 418-425.

Alisherovna, K. M., Khabibovna, Y. S., Nizamitdinovich, K. S., & Bakhtiyorovich, U. J. (2023). CYSTATIN and KIDNEY FUNCTION. Journal of new century innovations, 38(2), 220-225.

Nizamitdinovich, K. S., Khabibovna, Y. S., Alisherovna, K. M., & Tashtemirovna, E. M. M. (2023). Spinal Injury for Rheumatoid Arthritis. Miasto Przyszłości, 40, 426-432.

Khabibovna, Y. S., Alisherovna, K. M., Erkinovna, K. Z., & Djamshedovna, K. D. (2023). Gender Characteristics of the Course of Rheumatoid Arthritis. Miasto Przyszłości, 40, 438-442.

Khabibovna, Y. S., Alisherovna, K. M., Tashtemirovna, E. M. M., Nizamitdinovich, K. S., & Abdukadirovna, A. S. (2023). ANTITHROMBOTIC THERAPY IN CARDIOLOGICAL PATIENTS. Journal of new century innovations, 39(1), 169-171.

Erkinovna, K. Z., Khabibovna, Y. S., & Abrorovna, V. N. (2023). MONITORING OF QUALITY OF LIFE IN PATIENTS WITH ARTERIAL HYPERTENSION OF OLDER AGE GROUPS. Academia Science Repository, 4(5), 276-285.

Xabibovna, Y. S., & Buriboevich, N. M. (2021, May). SOME FEATURES OF STRUCTURAL AND FUNCTIONAL CHANGES OF THE MYOCARDIAL IN PATIENTS WITH DIABETES MELLITUS WITH DIASTOLIC HEART FAILURE. In E-Conference Globe (pp. 208-211).

Yarmukhamedova, S. K., Normatov, M. B., & Amirova, S. A. (2021). Modification of structural and functional indicators of the heart in diabetes mellitus patients with diastolic heart failure. Journal of Advanced Medical and Dental Sciences Research, 9(5), 1-4.

Khabibovna, Y. S., Alisherovna, K. M., Totlibayevich, Y. S., & Davranovna, M. K. (2023). PAINLESS CARDIAC ISCHEMIA AND RHEUMATOID ARTHRIT. Journal of new century innovations, 29(1), 98-105.

Ziyadullaev, S. K., Sultonov, I. I., Dushanova, G. A., & Akbarovna, K. S. (2021). The Effectiveness Of Pharmacotherapy For Dmards With Ra Depending On The C3435t Polymorphism Of The Mdr1 Gene. Int. J. of Aquatic Science, 12(3), 2908-2916.

Islomovich, S. I., Alisherovna, K. M., & Djamshedovna, K. D. (2024). FACTORS OF OSTEOPOROSIS IN PATIENTS WITH CORONARY HEART DISEASE IN COMBINATION WITH RHEUMATOID ARTHRITIS. Ta'lim innovatsiyasi va integratsiyasi, 31(2), 132-138.

Islomovich, S. I. (2024). FEATURES OF THE COURSE OF PREGNANCY IN RHEUMATOID ARTHRITIS. International journal of medical sciences, 4(10), 77-84.

Alisherovna, K. M., Nizamitdinovich, K. S., & Islomovich, S. I. (2024). THERAPY OF RHEUMATOID ARTHRITIS DURING PREGNANCYTHE. Ta'lim innovatsiyasi va integratsiyasi, 31(2), 172-180.

Ilkhom, S. (2023). CAJAM–VOLUME 1. ISSUE 1. 2023. Central Asian Journal of Advanced Medicine, 1(01), 16-19.

Islomovich, S. I. (2024). GENDER CHARACTERISTICS OF THE CURRENT RHEUMATOID ARTHRITIS. International journal of medical sciences, 4(10), 3-8.

Djamshedovna, K. D., Alisherovna, K. M., & Islomovich, S. I. (2024). ARTERIAL HYPERTENSION IN RHEUMATOID ARTHRITIS. Ta'lim innovatsiyasi va integratsiyasi, 31(2), 139-145.

Nizamitdinovich, K. S., Alisherovna, K. M., & Islomovich, S. I. (2024). CLINICAL COURSE OF BRONCHIAL ASTHMA IN PATIENTS WITH THYROID DISEASES. Ta'lim innovatsiyasi va integratsiyasi, 31(2), 181-187.

Alisherovna, K. M., Nizamitdinovich, K. S., & Islomovich, S. I. (2024). FEATURES OF BONE MINERAL DENSITY IN PATIENTS WITH DISEASES OF THE DIGESTIVE SYSTEM. Ta'lim innovatsiyasi va integratsiyasi, 31(2), 162-171.

Alisherovna, K. M., Islomovich, S. I., & Djamshedovna, K. D. (2024). PSYCHOEMOTIONAL STATE AND QUALITY OF LIFE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS. Ta'lim innovatsiyasi va integratsiyasi, 31(2), 124-131.

Хамраева, Н. А., Султонов, И. И., & Хасанов, Ф. Ш. У. (2019). Кожные проявления у больных системной красной волчанкой. Вопросы науки и образования, (28 (77)), 128-131.

Sultonov, I. I., Kh, Z. S., Ruzybakieva, M. R., Kireev, V. V., Aripova, T. U., & Suyarov, A. A. (2021). Pharmacogenetic Aspects of Drug Resistance in Rheumatoid Arthritis. Annals of the Romanian Society for Cell Biology, 4147-4150.

Тоиров, А. Э., Султонов, И. И., & Тоиров, Э. С. (2020). ЗНАЧЕНИЕ ДИСФУНКЦИИ ПОЧЕК У БОЛЬНЫХ ОСТРЫМ ИНФАРКТОМ МИОКАРДА НА ФОНЕ САХАРНОГО ДИАБЕТА 2-ГО ТИПА. Вестник науки и образования, (9-3 (87)), 86-91.

Kireev, V. V., & Sultonov, I. I. (2021). Genetic Engineered Preparations-An Innovative Approach in the Treatment of Rheumatoid Arthritis. Annals of the Romanian Society for Cell Biology, 4114-4119.

Hamraeva, N. A., Sultonov, I. I., & Hasanov, F. S. (2020). Systemic lupus erythematosus treatment strategy. Journal of Critical Reviews, 7(9), 269-270.

Иргашева, У. З., Султонов, И. И., & Тоиров, Д. Р. (2013). Признаки дебюта системной красной волчанки. Академический журнал Западной Сибири, 9(1), 15-15.

Xasanov, F. S., & Sultonov, I. I. (2023). RHEUMATOID ARTHRITIS TREATED WITH DMARDS AND CARDIOVASCULAR DISEASE RISK. Oriental Journal of Medicine and Pharmacology, 3(02), 45-52.

Нурматова, Л., Султонов, И., & Тоиров, Э. (2011). Эффективность препаратов пищеварительной активности в комплексном лечении больных хроническим гепатитом. Журнал проблемы биологии и медицины, (3 (66)), 107-110.

Sultonov, I. I., Xasanov, F. S., Eshmuratov, S., Uralov, R. S., Shukurova, D., & Ziyadullayev, S. X. Predictors of Systemic Lupus Erythematosus: A Case-control Study. International journal of health sciences, 6(S10), 175-182.

Sultonov, I. I., Khamrayev, X. X., & Xasanov, F. SYSTEMIC LUPUS ERYTHEMATOSUS AND CARDIOVASCULAR PATHOLOGY: WHERE WE AT?.

Yarmukhamedova, S. K., Alisherovna, K. M., Tashtemirovna, E. M. M., & Nizamitdinovich, K. S. (2023). The Effectiveness of Trimetazidine in Arrhythmias. Miasto Przyszłości, 33, 215-221.

Khabibovna, Y. S., & Abdukodirovna, A. S. (2021). Changes in the diastolic function of the right ventricle in arterial hypertension.

Khabibovna, Y. S. (2020). Оценка Признаков Диастолической Дисфункции Правого Желудочка У Больных С Артериальной Гипертонией. Journal of cardiorespiratory research, 1(2), 88-92.