The aim of the study was to study the effect of enalapril and telmisartan on hemodynamic parameters, diastolic function (DF) of the left ventricle (LV) in patients with coronary heart disease (CHD) with concomitant arterial hypertension. Material: 51 patients (men) with a stable course of coronary heart disease, the average age is 57.3+3.4 years. Methods: general clinical and laboratory studies, daily blood pressure monitoring, Holter ECG monitoring, echocardiography. Results and conclusions: course therapy with additional inclusion telmisartan (micardis) in patients with coronary heart disease with LV diastolic dysfunction by type of abnormal relaxation allowed to improve the parameters of transmittal diastolic flow: IVRT values decreased to 25%, DT – up to 13.4%, the E/A ratio increased to 23%. Improvement in diastolic function was accompanied by a decrease in LV myocardial mass index to 5.6%, a decrease in daily myocardial ischemia; improvement in LV systolic function was noted: an increase in LV ejection fraction to 9.6%, a fraction of systolic shortening anterior-posterior LV size by 17.2%. Significant differences between the groups of patients with diastolic  dysfunction of the left ventricle are associated with the optimization of relaxation and conditions of filling of the left ventricle during early and late diastole.

coronary heart disease, diastolic dysfunction of the left ventricle, angiotensin receptor antagonists.

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