Postoperative pain remains a pressing issue in modern surgery. Safe and effective pain treatment in children requires, first of all, the availability of informative and reliable methods for its assessment. One of the main features of pain intensity and analgesia effectiveness assessment in pediatrics is the impossibility of active cooperation of pediatric patients during research. In pediatric practice, it is often necessary to work with newborns and young children who have not yet learned to speak, and in neurosurgery, clinicians encounter children with delayed psychomotor development, focal neurological symptoms (for example, in the form of damage to sensory and motor conductors, aphasia), which complicates or even makes it impossible to contact the patient and objectively control analgesia ( Oberlander T. F. , Gilbert​ C. A. , Chamber​ S. T. et​​ al ., 1999). At the same time, it is in pediatric patients, due to the immaturity of the nervous system developing in the postnatal period, that uncontrolled pain leads to the development of inadequate stress responses with changes in protein metabolism, weakening of the immune response and the formation of pathological reactions to pain in the distant future ( Wolf A., 2003).

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