Patients with long-term persistent symptoms after COVID-19 infection remain to this day the center of ongoing discussions regarding the choice of further treatment tactics. One of the most common manifestations of post-coronavirus syndrome is organizing pneumonia (OP). Determining additional biological markers of the severity of lung damage in AP has diagnostic value for timely correction of therapy in order to improve the prognosis of the disease. At the present stage, biological markers of severity are widely used in clinical practice, such as C-reactive protein, ferritin, D-dimer, lactate dehydrogenase, creatine kinase, procalcitonin, interleukin-6, NTproBNP/BNP (N-terminalpro B-typenatriureticpeptide, B-typenatriureticpeptide /B-typenatriureticpeptide) and troponin. The article will present the results of our own studies of post-Covid patients with AP to determine significant markers for diagnosing the severity of the condition.

coronavirus infection, COVID-19, post-Covid syndrome, organizing pneumonia, biological markers of severity.

Aitbaev K.A., Murkamilov I.T., Fomin V.V., et al. SARS-COV-2 coronavirus: epigenetic mechanisms of susceptibility and possibilities of epidrug prophylaxis // TheScientific Heritage.2021.№62-2 (62).P.16-20.DOI:10.24412/9215-0365-2021-62-2-16-20

Aitbaev K.A., Murkamilov I.T., Fomin V.V., et al. Severe respiratory viral infections: epigenetic mechanisms of predisposition and possibilities of epigenetic-targeted therapy // Bulletin of Science and Practice.2021.V.7.№ 3.P. 136-160.DOI:10.33619/2414-2948/64/13

Budchanov Yu.I. Cellular immunity. Types of cellular cytotoxicity. Receptors and markers, lymphocyte subpopulations // Textbook on general immunology. Tver 2008.P.11.

Vitkina T.I., Sidletskaya K.A. The role of interleukin-6 signaling in the development of systemic inflammation in chronic obstructive pulmonary disease // Bulletin of Physiology and Pathology of Respiration.2018.№.69.P.97-106. DOI:10.12737/article_5b98.

Koroleva O.S., Zateyshchikov D.A. Biomarkers in cardiology: registration of intravascular inflammation. // Pharmateka. – M., 2007. - No. 8/9. - pp. 30-36.

Repina V.P. Effect of catecholamines on the immune status of practically healthy people // Man and his health. Fundamental and clinical medicine: 10. All-Russian med-biological conf. - SPb, 2007.-P.374-375.

Khuzhamberdiev M.A., Boymirzaev M. Disorders of the sympathetic-adrenal system in large-focal myocardial infarction. // Medical journal of Uzbekistan. - T., 2001. - No. 4. - P. 26-28.