General anesthesia is understood as a change in the physiological state, characterized by reversible loss of consciousness, complete analgesia, amnesia and some degree of muscle relaxation [6,15]. The introduction of anesthetics into the body is accompanied by changes in all vital organs and systems. The degree of these changes depends on many factors: chemical, pharmacodynamic properties of the anesthetic, concentration, duration of action, age of the patient, nature, severity of the disease, etc. [61]. In addition to the analgesic effect, general anesthesia has a number of side effects. The main target of anesthetics is the central nervous system.

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