Articles
| Open Access |
https://doi.org/10.55640/
EFFICACY IN EASING PRIMARY DYSMENORRHEA PAIN AMONG ADOLESCENTS
Ndari Dumadi , Faculty of Medicine, Universitas Sebelas Maret, IndonesiaAbstract
This study investigates the potential efficacy of a pineapple and ginger elixir in alleviating primary dysmenorrhea pain among adolescents. Primary dysmenorrhea, characterized by painful menstrual cramps, is a common gynecological condition affecting young women. Pineapple and ginger have been traditionally used for their anti-inflammatory and analgesic properties. In this randomized controlled trial, adolescent participants experiencing primary dysmenorrhea were administered either a pineapple and ginger drink or a placebo. Pain intensity and duration were assessed before and after intervention using standardized pain scales. Preliminary findings suggest that the pineapple and ginger elixir may offer significant relief from primary dysmenorrhea pain compared to the placebo. Further research is warranted to validate these results and explore the underlying mechanisms of action.
Keywords
Primary dysmenorrhea, Menstrual pain, Pineapple
References
Agostinis C, Zorzet S, De Leo R, Zauli G, De Seta F, Bulla R (2015). The com-bination of N-Acetyl cysteine, Alpha-lipoic acid, and bromelain shows high anti-inflammatory properties in novel in vivo and in vitro models of Endo-metriosis. Mediator of Inflammation, 2015: 1-9.
Al-Asadi JN,Abdul-Quadir RA (2013). Dys-menorrhoea and its impact on daily routine activities among secondary school students in Basra, Iraq. J Fac Med Baghdad, 55 : 339-344.
Ali BH, Blunden G, Tanira MO, Nemmar A (2008). Some phytochemical, phar-macological dan toxicological proper-ties of ginger (Zingiber officinale Roscoe): a review of recent research. Food Chemical Toxicology, 46(2): 409–420.
Bernardi M, Lazzeri L, Perelli F, Reis FM, Petraglia F (2017). Dysmenorrhea and related disorders: Review. F1000re-search, 6: 1-7.
Bhui K, Prasad S, George J, Shukla Y (2009). Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation trigger-ing mitochondrial death pathway. Cancer Lett, 282: 167-176.
Bolten WW, Glade MJ, Raum S, Ritz BW (2015). The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: A randomized, double-blind, placebo-controlled trial. Arthritis, 25: 15-21.
Contreras A, Paape MJ, Miller RH, Corrales JC, Luengo C, Sanchez A (2008). Effect of bromelain on milk yield, milk composition, dan mammary health in dairy goats. Tropical Animal Health Production, 41: 493-498.
Chen CX, Barrett B, Hindawi KLK (2016). Efficacy of Oral Ginger (Zingiber offi-cenale) for Dysmenorrhea: A Syste-matic Review and Meta-Analysis. Publishing Corporation Evidence-Based Complementary and Alterna-tive Medicine, 57: 1-10.
Dighe NS, Pattan SR, Merekar AN, Laware RB, Bhawar SB, Nirmal SN, Gaware VM, Hole MB, Musmade DS (2010). Bromelain A Wonder Supplement: A Review. Pharmacologyonline, 1: 11-18.
Dugasani S, Pichika MR, Nadarajah VD, Balijepalli MK, Tandra S, Korlakunta JN. 2010. Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol.Journal of Ethno-pharmacology,127:515–520.
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