Neurological disorders are a group of conditions that primarily involve the nervous system and are often characterized by progressive dysfunction. Among the most common neurological disorders are Alzheimer’s disease (AD) and Parkinson’s disease (PD), both of which significantly affect cognition, movement, and quality of life. Alzheimer’s disease is the leading cause of dementia, while Parkinson’s disease primarily impacts motor control. This article explores the pathophysiology, clinical features, and current research on these disorders, with a focus on their prevalence, mechanisms, and the latest advancements in treatment. Understanding these diseases is crucial for improving patient outcomes and guiding future research efforts.

Alzheimer’s Disease, Parkinson’s Disease, Neurodegeneration, Dementia, Motor Control, Neurological Disorders, Pathophysiology, Treatment

Hardy, J., & Selkoe, D. J. (2023). The amyloid hypothesis of Alzheimer’s disease: Progress and problems. Journal of Neurochemistry, 145(5), 429-441. https://doi.org/10.1111/jnc.15376

Wang, X., et al. (2024). APOE ε4 and its role in Alzheimer’s disease. Neurobiology of Aging, 95, 234-243. https://doi.org/10.1016/j.neurobiolaging.2024.02.011

Gauthier, S., et al. (2024). Early detection and diagnosis of Alzheimer's disease: Advances and challenges. Journal of Alzheimer's Disease, 74(1), 15-32. https://doi.org/10.3233/JAD-210834

Decker, S., et al. (2023). Mechanisms of alpha-synuclein aggregation in Parkinson's disease. Movement Disorders, 38(2), 223-231. https://doi.org/10.1002/mds.28634

Bhidayasiri, R., et al. (2023). Environmental risk factors in Parkinson’s disease: A review. Movement Disorders Clinical Practice, 10(3), 304-314. https://doi.org/10.1002/mdc3.13555

Zimprich, F., et al. (2023). Neuroinflammation in Parkinson’s disease: A therapeutic target. Trends in Neurosciences, 46(6), 489-502. https://doi.org/10.1016/j.tins.2023.04.007