This article explores the potential effects of Rifampicin on hearing in patients recovering from brucellosis. While Rifampicin remains a cornerstone in the treatment of brucellosis, concerns have emerged regarding its possible ototoxicity. The review evaluates whether auditory complications stem from the drug itself or from brucellosis-induced neurological damage, particularly neurobrucellosis. Clinical data suggest that Rifampicin, when used alone, is not significantly associated with hearing loss. However, the risk increases when combined with other ototoxic agents such as aminoglycosides. The article emphasizes the importance of audiological monitoring in patients with neurological symptoms and advocates for cautious use of combination therapies.

brucellosis, rifampicin, hearing loss, ototoxicity, neurobrucellosis, sensorineural hearing loss, antibiotic therapy, aminoglycosides, audiometry, auditory monitoring.

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