Articles | Open Access | https://doi.org/10.55640/

EVALUATION OF THE EFFECTIVENESS OF THE PEPTIDE COMPOSITION OF THE CALIFORNIAN WORM EXTRACT ON THE IMMUNE SYSTEM

Saidov Shokhrullo Sharofullaevich, Abdikarimova Shakhnoza Khuzhakulovna, Sheralieva Shakhodat Khamraevna, Ergasheva Mamura Bahodirovna, Chultanova Aziza Abdullaevna , TMA Termez branch of the Department of Medical Biology and Histology

Abstract

Modern biotechnology is actively exploring natural biologically active compounds, such as peptides, to develop effective means of strengthening the immune system. One promising source of such compounds is the extract of the Californian worm (Lumbricus rubellus), which has a unique composition of peptides. This article discusses the main methods for assessing its effect on the immune system, including in vitro and in vivo studies.

Keywords

Californian worm extract, peptides, immune system, immunomodulation, cytokines. In this version, the text became more natural, but at the same time retained scientific accuracy. If you need to change something else - style, level of formality or structure - tell me, and I will help to improve it.

References

Levinskaya, A. A., Kuznetsov, I. V. "Peptides as Promising Biologically Active Substances." Biotechnology, 2020, No. 5, pp. 23-31.

Li, X., Liu, S., Fang, Q., et al. "Immunomodulatory effects of peptides derived from earthworm extract on macrophages." Journal of Ethnopharmacology, 2019, Vol. 236, pp. 205-212.

Kuzmin, N. S., Ivanova, E. P. "Immunomodulatory properties of natural compounds." Medical Immunology, 2021, Vol. 23, No. 2, pp. 103-112.

Zhang, Y., Wang, Z., Wang, L. "Bioactive peptides from Lumbricus rubellus: Isolation, characterization, and potential applications." Peptides, 2022, Vol. 145, pp. 104223.

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EVALUATION OF THE EFFECTIVENESS OF THE PEPTIDE COMPOSITION OF THE CALIFORNIAN WORM EXTRACT ON THE IMMUNE SYSTEM. (2025). International Journal of Medical Sciences, 5(05), 331-332. https://doi.org/10.55640/