Hyperprolactinemia is a persistent elevation of prolactin levels in the blood serum. The hyperprolactinemia syndrome is a symptom complex that arises against the background of hyperprolactinemia, the most characteristic manifestation of which is impaired reproductive function. The causes of hyperprolactinemia can be diverse, both endogenous and exogenous. The primary method of treatment is dopamine agonist therapy; in the case of tumor genesis, surgical and radiation methods are also used. About 15% of patients exhibit resistance to dopamine agonists, which necessitates the development of individualized treatment approaches. Timely diagnosis and a properly selected therapeutic strategy play a crucial role in preventing pathological changes caused by hyperprolactinemia.

Hyperprolactinemia, prolactinoma, pituitary adenoma, dopamine agonists, therapy resistance, reproductive system, benign breast dysplasia, anovulation.

Korneeva I.E. Clinic, diagnosis and treatment of infertility in women with functional hyperprolactinemia.

Dedov I.I., Mel’nichenko G.A., Dzeranova L.K., Pigareva E.K. Federal Clinical Guidelines for Hyperprolactinemia.

Maksimova A.V., Pinigina Y.I., Stroev Y.I. Hypothyroidism, prolactin, and the female reproductive system.

Varlamova T.M., Sokolova N.N. Women's reproductive health and thyroid function insufficiency.