Hepatitis C virus (HCV) infection remains a significant global health challenge due to its high prevalence and potential progression to chronic liver disease, cirrhosis, and hepatocellular carcinoma. While antiviral medications have revolutionized treatment outcomes, interest persists in complementary approaches, including the use of folk (traditional) medicine. This article aims to explore the historical background, commonly used folk remedies, potential mechanisms of action, and the need for further scientific validation of folk medicinal practices in the context of Hepatitis C. Furthermore, it underscores the importance of integrated approaches that combine evidence-based medicine with culturally sensitive traditional practices, highlighting both the opportunities and risks.

folk medicine, traditional remedies, herbal therapy, milk thistle, antiviral activity, liver health

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