
SPECTROPHOTOMETRIC ANALYSIS OF 2-PHENOXYETHYLDIMETHYLBENZYLAMMONIUM-2-OXYNAPHTHOATE AND ITS CORRELATION WITH ANTIPARASITIC ACTIVITY
Xamdamova Shahnoza Baxtiyor kizi,Pardayev Ulug‘bek Xayrullo ugli,Kosimova Xurshida Rajabboyovna , Uzbekistan-Finland Pedagogical Institute.Abstract
his study investigates the spectrophotometric characteristics of 2-phenoxyethyldimethylbenzylammonium-2-oxynaphthoate (PEDBA-ONA), a compound with promising antiparasitic potential. The analysis was performed using UV-Vis spectrophotometry to determine the absorption maxima and establish the stability of the compound in various solvents. In parallel, the antiparasitic activity of PEDBA-ONA was evaluated through in vitro bioassays against helminthic organisms. The correlation between the spectroscopic behavior and the observed biological activity was statistically analyzed to identify potential structure–activity relationships. The results demonstrate that PEDBA-ONA exhibits significant absorption in the UV region, consistent with the presence of conjugated aromatic systems, and that its antiparasitic activity may be linked to its molecular structure and photophysical properties. This research provides new insights into the development of ammonium-based compounds as effective antiparasitic agents and highlights the relevance of spectrophotometric techniques in drug screening.
Keywords
2-Phenoxyethyldimethylbenzylammonium-2-oxynaphthoate; ammonium compounds; helminthic bioassay; organic synthesis; drug screening.
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