Articles | Open Access | https://doi.org/10.55640/

TITLE OF THE ARTICLE: POST-VACCINATION IMMUNITY TO MEASLES IN CHILDREN WITH POST-COVID SYNDROME

Kenzhayeva Dilorom Toshtemirovna,Akhmadova Durdona Kamol kizi , Termez Branch of the Tashkent Medical Academy

Abstract

 This article examines the impact of post-COVID syndrome on post-vaccination immunity to the measles virus in children. A total of 89 children undergoing outpatient and inpatient treatment were examined between 2024 and 2025. Post-COVID syndrome was diagnosed by ELISA testing for IgG antibodies to SARS-CoV-2, and immunity to measles was assessed using the VectoMeasles-IgG ELISA test. A decrease in measles-specific antibody titers was found in previously vaccinated children with post-COVID syndrome. The study highlights the importance of monitoring and revaccination in cases of seronegative results.

Keywords

measles, vaccination, post-vaccination immunity, post-COVID syndrome, IgG antibodies, SARS-CoV-2, ELISA, children, revaccination, immune status, VectoMeasles, epidemiology, seronegativity, post-COVID immunity, prevention

References

Baranov A.A., Aleynikova E.N. Post-COVID Syndrome in Children and Adolescents. — Pediatrics, 2022, No. 3, pp. 25–31.

Brylyakova E.A., Frolov A.F. Measles: Current Situation and Prevention. — Infectious Diseases, 2021, No. 2, pp. 14–19.

Temporary Guidelines of the Ministry of Health of the Russian Federation. “Features of COVID-19 in Children”, 2023.

State Research Center for Virology and Biotechnology “Vector”. User Manual for VectoMeasles-IgG ELISA Test. — Novosibirsk, 2024.

World Health Organization. Measles vaccines: WHO position paper – April 2023. Weekly Epidemiological Record, 2023; 98(14): 129–144.

Litvinova E.A. Post-Vaccination Immunity: Challenges and Solutions. — Journal “Immunology”, 2022, No. 1, pp. 5–11.

Akhmedova S.Sh., Rakhimova F.T. Diagnosis and Prevention of Measles in the Post-Pandemic Period. — Tashkent, 2023, pp. 42–47.

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TITLE OF THE ARTICLE: POST-VACCINATION IMMUNITY TO MEASLES IN CHILDREN WITH POST-COVID SYNDROME. (2025). International Journal of Medical Sciences, 5(06), 80-82. https://doi.org/10.55640/