Coxarthrosis, or osteoarthritis of the hip joint, is a chronic degenerative disease that significantly affects mobility and quality of life. Recent research has emphasized the role of genetic inheritance in the onset and progression of this condition. This review examines the hereditary transmission of coxarthrosis, highlighting key genes such as COL2A1 and GDF5 that contribute to cartilage degeneration. In addition to discussing medical implications, the article explores the social and economic burdens associated with early-onset hereditary coxarthrosis. The importance of early diagnosis, lifestyle modification, and preventive measures is underscored to minimize disease progression and improve patient outcomes.

Coxarthrosis; Heredity; Osteoarthritis; Genetic predisposition; Public health; Preventive strategies; Cartilage degeneration.

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