Articles | Open Access | https://doi.org/10.55640/

THE CHEMICAL BASIS FOR THE DEVELOPMENT OF NEW AGROCHEMICAL PREPARATIONS BASED ON ACRYLONITRILE

Pardayev Ulug‘bek Xayrullo ugli,Mirsaliyeva Maftuna Azamat kizi,Yaxshinorova Nafisa Asliddin kizi,Khusanov Eldor Safariddinovich , Uzbekistan-Finland Pedagogical Institute.

Abstract

Acrylonitrile, a reactive vinyl nitrile compound, has garnered increasing attention in agrochemical research due to its structural versatility and potential bioactivity. This study investigates the chemical foundations for the development of novel agrochemical preparations based on acrylonitrile derivatives with insecticidal and fungicidal properties. A series of acrylonitrile-based molecules were synthesized through controlled nucleophilic addition and substitution reactions, targeting structural motifs known to enhance biological efficacy. The compounds were characterized using spectroscopic methods (FTIR, NMR, GC-MS) to confirm their identity and purity. Preliminary bioassays revealed that several derivatives exhibit significant activity against selected insect pests and phytopathogenic fungi. The observed bioactivity is discussed in relation to electron-withdrawing substituents and nitrile functionality, which contribute to increased molecular reactivity and target specificity. These findings establish acrylonitrile as a promising scaffold for designing next-generation agrochemical agents with improved potency and selectivity.

Keywords

References

Шамшурин, А. А., & Кример, М. З. (1976). Физико-химические свойства пестицидов: Справочник (с. 3-11). Москва: Химия.

Xayrullo o'g P. U. et al. The essence of the research of synthesis of natural indicators, studying their composition and dividing them into classes //fan va ta'lim integratsiyasi (integration of science and education). – 2024. – Т. 1. – №. 3. – С. 50-55.

Lin, X., Zhao, Y., Zhang, J., & Chen, L. (2018). Synthesis and insecticidal evaluation of novel acrylonitrile-containing pyrazole derivatives. Pesticide Biochemistry and Physiology, 148, 36–42.

Zhao, H., Li, M., Wu, Q., & Yang, J. (2020). Design and antifungal activity of acrylonitrile-substituted phenyl ethers against crop pathogens. Crop Protection, 136, 105230.

XORIDDINOVICH I. Y., NORMAKHMAT Y. Determination of the Adoption Characteristiscs of Activated Carbon on the Basis of Nut Seeds //International Journal of Innovations in Engineering Research and Technology. – Т. 7. – №. 4. – С. 1-5.

Hansch, C., Leo, A., & Hoekman, D. (1995). Exploring QSAR: Hydrophobic, electronic, and steric constants. Washington, DC: American Chemical Society.

Khoriddinovich I. Y. et al. Purification of spent methyldiethanolamine solutions with activated carbon au-ko. – 2023.

Tomlin, C. D. S. (Ed.). (2009). The Pesticide Manual (15th ed.). Alton, UK: British Crop Protection Council.

Yusuf I. et al. DEVELOPMENT OF TERMOCHEMICAL CARBON ADSORBENTS BASED ON FRUIT SEEDS AND APPLICATION IN SORPTION OF RARE METALS //Universum: технические науки. – 2022. – №. 10-7 (103). – С. 4-8.

Zhang, M., Wang, S., & Liu, T. (2021). Advances in the development of nitrile-based agrochemicals: Design strategies and environmental considerations. Journal of Agricultural and Food Chemistry, 69(24), 6781–6794.

Xayrullo o'g P. U. et al. Using natural plant extracts as acid-base indicators and pKa value calculation method //fan va ta'lim integratsiyasi (integration of science and education). – 2024. – Т. 1. – №. 3. – С. 80-85.

Nurmonova E., Berdimuratova B., Pardayev U. DAVRIY SISTEMANING III A GURUHI ELEMENTI ALYUMINIYNING DAVRIY SISTEMADA TUTGAN O ‘RNI VA FIZIK-KIMYOVIY XOSSALARINI TADQIQ ETISH //Modern Science and Research. – 2024. – Т. 3. – №. 10. – С. 517-526.

Khusanov E. S. et al. Solubility of Components in the Acetic Acid–Triethanolamine–Water System //Russian Journal of Inorganic Chemistry. – 2023. – Т. 68. – №. 11. – С. 1674-1680.

Бобожонов Ж. Ш., Шукуров Ж. С., Тогашаров А. С. Растворимость системы тетракарбамидохлората кальция-ацетат аммония-вода //Universum: технические науки. – 2022. – №. 4-8 (97). – С. 30-33.

Jiemuratova A., Pardayev U., Bobojonov J. COORDINATION INTERACTION BETWEEN ANTHRANILIC LIGAND AND D-ELEMENT SALTS DURING CRYSTAL FORMATION: A STRUCTURAL AND SPECTROSCOPIC APPROACH //Modern Science and Research. – 2025. – Т. 4. – №. 5. – С. 199-201.

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THE CHEMICAL BASIS FOR THE DEVELOPMENT OF NEW AGROCHEMICAL PREPARATIONS BASED ON ACRYLONITRILE. (2025). International Journal of Medical Sciences, 5(06), 250-257. https://doi.org/10.55640/