This study examined the relationship between thyroid-stimulating hormone (TSH) levels and the severity of clinical symptoms of primary hypothyroidism in women after strumectomy. Data from 64 women who underwent total or subtotal strumectomy were analyzed. Symptom severity was assessed using a 10-point clinical scoring scale. A significant positive correlation between elevated TSH levels and symptom intensity was observed, especially among patients after total strumectomy. The findings support the importance of regular laboratory follow-up and individualized treatment planning.

hypothyroidism, TSH, clinical severity, hormonal imbalance, strumectomy

Jonklaas J. et al. Guidelines for the treatment of hypothyroidism. Thyroid. 2014.

Gharib H. et al. Subclinical hypothyroidism: a review. JAMA. 2020.

Taylor P.N. et al. Relationship between TSH and symptoms. Clin Endocrinol. 2019.

Pearce S.H.S. Clinical relevance of TSH elevation. Endocr Rev. 2020.

Biondi B. Biochemical markers in hypothyroidism. J Clin Endocrinol Metab. 2021.

Razvi S. et al. TSH thresholds and treatment. Lancet Diabetes Endocrinol. 2022.

Shakir M.K.M. et al. TSH levels and fatigue. Med Clin North Am. 2023.

McLeod D.S.A. Clinical utility of symptom scores. Thyroid Res. 2020.

Zimmermann M.B. Hormonal evaluation post-surgery. Hormones. 2018.

Haugen B.R. Clinical guidelines in hypothyroidism. Thyroid. 2016.

Wiersinga W.M. Diagnostic approach in thyroid dysfunction. Eur Thyroid J. 2017.

Duntas L.H. Patient-tailored hypothyroid management. Horm Metab Res. 2020.

Ito Y. Postoperative monitoring in thyroid surgery. J Endocr Surg. 2021.

Lim H. Predictive value of TSH. BMC Endocr Disord. 2019.

Vanderpump M.P.J. Epidemiology of hypothyroidism. Lancet. 2021.