Leukoplakia of the oral mucosa (OM) is the most common potentially malignant disease characterized by the appearance of white, non-erasable spots that have no alternative clinical and histological diagnosis. The article presents modern concepts of the etiology, pathogenesis, classification, clinical forms, diagnostics and treatment of leukoplakia. Particular attention is paid to the issues of dysplasia and precancerous potential of the disease. A review of modern approaches to therapy and dispensary observation of patients with this disease is conducted.

leukoplakia, oral mucosa, dysplasia, precancerous disease, treatment.

Saidova M., Inoyatov A. Trophic ulcer of the oral mucosa as a complication of covid-19 // Days of Young Scientists. - 2022. - No. 1. - P. 301-302.

Kamilov H. et al. Clinical picture, diagnosis and treatment of chronic recurrent aphthous stomatitis // Stomatologiya. - 2021. - No. 2 (83). - P. 64-67.

Kadyrbaeva A., Azimova A., Sadikova I. Comparative assessment of complex treatment of traumatic ulcers of the oral mucosa // Actual problems of dentistry and maxillofacial surgery. - 2022. - No. 1. – P. 393-394

Inoyatov A., Saidova M. Microcirculatory disorders in patients with post-covid syndrome and trophic ulcers of the oral mucosa // Medical science of Uzbekistan. – 2023. – No. 1. – P. 06-0Owczarek-Drabińska JE, Nowak P, Zimoląg-Dydak M, Radwan-Oczko M. The Prevalence of Oral Mucosa Lesions in Pediatric Patients. //Int J Environ Res Public Health. 2022 Sep 8;19(18):11277

Erbaş GS, Botsali A, Erden N, Arı C, Taşkın B, Alper S, Vural S. COVID-19-related oral mucosa lesions among confirmed SARS-CoV-2 patients: a systematic review. //Int J Dermatol. 2022 Jan;61(1):20-32.

Azatyan V, Yessayan L, Khachatryan A, Perikhanyan A, Hovhannisyan A, Shmavonyan M, Ghazinyan H, Gish R, Melik-Andreasyan G, Porksheyan K. Assessment of pathomorphological characteristics of the oral mucosa in patients with HBV, HCV and HIV.// J Infect Dev Ctries. 2021 Nov 30;15(11):1761-1765.