Psoriasis is a genetically determined chronic skin disorder of multifactorial origin, characterized by a recurrent course and immune-mediated inflammation, often accompanied by musculoskeletal involvement. It is considered one of the most common dermatological conditions. According to the World Health Organization (WHO), the global prevalence of psoriasis ranges from 0.5% to 5.5% of the general population, depending significantly on the climate and geographic region [1]. In recent years, psoriasis has increasingly been classified as a systemic disease due to its impact not only on the skin but also on joints, kidneys, and the liver—hence the term "psoriatic disease." Despite extensive research, the exact etiology of psoriasis remains unclear. The disease is characterized by epidermal hyperproliferation, impaired keratinocyte differentiation, and immune system dysregulation, leading to the production of immune-dependent cytokines and mediators that trigger inflammatory responses in the dermis [2]. Emotional stress and the psycho-emotional state of the patient are considered major triggering factors. In addition, chronic infections can provoke the initial manifestation of psoriasis. The disease frequently develops at sites of mechanical skin trauma—such as cuts, scratches, injections, abrasions, or burns—or after the use of certain medications (e.g., beta-blockers, non-steroidal anti-inflammatory drugs, or interferon). Climatic conditions also play a significant role; almost all patients report that sun exposure has a beneficial effect on their symptoms [1]. In recent years, novel and highly effective treatments based on the pathogenesis of the disease have been developed. Although these therapies may not lead to a complete cure, they help eliminate scaling lesions, which are a major factor in the reduction of patients' quality of life [3]. Treatment typically involves a comprehensive approach, including systemic and topical therapies, as well as physiotherapeutic procedures. When choosing the appropriate treatment method, clinicians take into account the stage of the disease, its clinical form, seasonal type (summer or winter), extent of skin involvement, comorbid conditions, and the patient’s age [Olisova O.Yu. et al., 2020].

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