Goal. Analysis of the prevalence and structure of mental disorders among patients with systemic lupus erythematosus (SLE).

Material and methods. 115 patients with reliable SLE aged 34 (24-45) years (median and interquartile range) were included, the duration of the disease was 8

(4-17) years old. The activity of SLE was assessed using the SLEDAI scale. Mental disorders were diagnosed by a psychiatrist in accordance with ICD-10 using a number of psychiatric and psychological scales.

Results. Mental disorders were detected in 76 out of 115 (66%) patients. Anxiety-depressive spectrum disorders prevailed (83%): depressive episodes (40%), adjustment disorders (24%), generalized anxiety disorders (10%) and dysthymia (9%). Severe cognitive impairment was detected in 7% of patients. There were no differences in age, gender, duration and degree of SLE activity, duration and cumulative dose of HA and cytotoxics in patients with and without mental disorders.

Conclusion. Mental disorders are common among patients with SLE (66%). In their anxiety and depressive disorders occupy the main place in the spectrum (83%). The nature of the relationship between SLE and mental disorders requires further study.

Systemic lupus erythematosus, mental disorders.

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