Systemic scleroderma (SSD) is a systemic disease based on microcirculation disorders, inflammation and generalized fibrosis. Interstitial lung disease (IPL) is one of the main manifestations of SSD. Determining the activity and severity of SSD is difficult, since it is very difficult to distinguish between fibrous and inflammatory changes, which in most cases are interrelated and have a similar clinical picture.

The aim of the study was to evaluate the value of the activity index (IA) and the total severity index (SIT) for the dynamic observation of patients with SDS with different course of IPL.

Systemic scleroderma; interstitial lung lesion; atherogenicity index; total severity index.

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