This article will highlight the scientific and practical importance of DNK Diagnostics and genetic screening in modern medicine. Thanks to advances in Molecular Biology, the possibilities of detecting genetic diseases, diagnosing them at an early stage and individual treatment are expanding. The study examined DNK analysis methods — polymerase chain reaction, high conductive sequencing, microarray technologies, and the effectiveness of prenatal and neonatal screening programs. The clinical applications of these processes, their role in the health care system, economic and ethical aspects were also analyzed. The results obtained show that the widespread introduction of genetic screening programs is important in improving the general health of the population, treating diseases at an early stage and developing the concept of individual medicine.

DNK diagnostics, genetic screening, molecular diagnostics, medical genetics, prenatal screening.

Strachan T., Read A. P. Human Molecular Genetics. 4th ed. Garland Science, 2018.

Brown T. A. Gene Cloning and DNA Analysis: An Introduction. 7th ed. Wiley-Blackwell, 2016.

Hariri R. et al. Next-Generation Sequencing in Clinical Diagnostics. Journal of Medical Genetics, 2020.

Chiu R. W. K., Lo Y. M. D. Noninvasive prenatal testing using cell-free fetal DNA. New England Journal of Medicine, 2014.

O‘zbekiston Respublikasi Sog‘liqni saqlash vazirligi. Genetika va molekulyar diagnostika bo‘limi darslik materiallari. Toshkent, 2019.

Toshkent Davlat Tibbiyot Universiteti. Genetika kafedrasi o‘quv qo‘llanmasi. Toshkent, 2021.

Islomov A., Rasulova N. Genetik skrining: amaliy jihatlar. Tibbiyot jurnal, 2020; 12(3):45-52.

World Health Organization. Genomics and World Health. WHO, 2019.