Severe periodontitis is a significant global health issue affecting a large portion of the population, leading to tooth loss, impaired masticatory function, and a reduced quality of life. Traditional surgical treatment methods are not always capable of completely regenerating lost periodontal tissues or guaranteeing long-term stable outcomes. Therefore, the improvement and optimization of existing surgical protocols using modern technologies—including guided tissue regeneration (GTR), growth factors, laser technologies, and microsurgical approaches—represent one of the most pressing tasks in modern dentistry. This research is aimed at enhancing clinical outcomes by analyzing combinations of different methods and developing the most effective treatment algorithms.

severe periodontitis, surgical treatment, guided tissue regeneration, growth factors, laser therapy, periodontal regeneration, microsurgery.

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