Articles | Open Access | https://doi.org/10.55640/

IMMUNE THROMBOCYTOPENIC PURPURA

Kholmurot Kurbonovich Mamadiev , Pediatric Infectious Disease Specialist, Pediatric Hematologist.

Abstract

Immune Thrombocytopenic Purpura (ITP) is an autoimmune hematological disorder characterized by a decreased platelet count due to immune-mediated destruction. This article explores the etiology, pathogenesis, clinical features, diagnostic approaches, and treatment strategies for ITP in children. The study emphasizes early diagnosis and individualized management to prevent hemorrhagic complications and improve patients’ quality of life.

Keywords

Immune thrombocytopenic purpura, autoimmune disease, platelet destruction, hemorrhagic syndrome, pediatric hematology

References

Neunert, C., Terrell, D. R., Arnold, D. M., et al. (2019). American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Advances, 3(23), 3829–3866.

Provan, D., Arnold, D. M., Bussel, J. B., Chong, B. H., Cooper, N., Gernsheimer, T., & Cheng, G. (2023). Updated international consensus report on the investigation and management of primary immune thrombocytopenia (ITP). Blood Reviews, 58, 101016.

Lambert, M. P., & Gernsheimer, T. B. (2021). Clinical updates in adult and pediatric immune thrombocytopenia. Hematology/Oncology Clinics of North America, 35(6), 1173–1187.

Rodeghiero, F., Carli, G., & Ruggeri, M. (2020). Immune thrombocytopenia in children and adults: What’s new? Seminars in Hematology, 57(1), 14–22.

Cines, D. B., & Blanchette, V. S. (2020). Immune thrombocytopenic purpura. New England Journal of Medicine, 383(10), 945–958.

Audia, S., Mahevas, M., Samson, M., Godeau, B., & Bonnotte, B. (2021). Pathogenesis of immune thrombocytopenia. Autoimmunity Reviews, 20(2), 102578.

Zeng, Y., Xiang, Y., Xu, J., et al. (2022). Epidemiology and treatment outcomes of pediatric ITP: A multicenter retrospective study. Pediatric Blood & Cancer, 69(10), e29783.

Article Statistics

Downloads

Download data is not yet available.

Copyright License

Download Citations

How to Cite

IMMUNE THROMBOCYTOPENIC PURPURA. (2025). International Journal of Medical Sciences, 5(10), 293-296. https://doi.org/10.55640/