liver pathologies significantly change the internal structure of hepatocytes, in particular, the state of their organelles. These changes are associated with impaired liver function and impaired cellular metabolism. In general, disorders of hepatocyte organelles lead to impaired metabolic and detoxification functions of liver cells, cell death, and the development of tissue fibrosis. These pathological processes are common in chronic forms of liver diseases, in particular in cirrhosis and hepatitis.

hepatocyte, liver pathology, organelle changes, mitochondrial dysfunction, endoplasmic reticulum stress, Golgi apparatus disorders, lysosome activity, lipid steatosis, cell necrosis, apoptosis, nuclear changes, fibrosis, metabolic dysfunction, chronic hepatitis, cirrhosis.

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