Articles | Open Access | https://doi.org/10.55640/

ADVANCED TECHNIQUES FOR EARLY BREAST CANCER DIAGNOSIS

Tilavov Tolibjon Bakhtiyor ugli , Asia International University, Bukhara, Uzbekistan

Abstract

Breast cancer remains the most common malignancy among women worldwide and a leading cause of cancer-related mortality. Early detection plays a crucial role in improving survival rates and treatment outcomes. In recent years, significant advances have been made in diagnostic technologies that enhance the sensitivity and specificity of early breast cancer screening. Traditional imaging techniques such as mammography, ultrasound, and magnetic resonance imaging (MRI) continue to serve as the cornerstone of detection; however, new modalities including digital breast tomosynthesis, molecular breast imaging, and contrast-enhanced mammography have demonstrated superior diagnostic accuracy (Smith, 2020; Johnson et al., 2021). Furthermore, non-invasive biomarkers, liquid biopsy, and artificial intelligence–based image analysis are emerging as promising tools for early-stage diagnosis (Lee & Kim, 2022; Brown et al., 2023). This literature review aims to analyze current diagnostic strategies, evaluate their clinical effectiveness, and discuss the potential of innovative technologies in transforming early breast cancer detection. Understanding these modern approaches provides a foundation for developing personalized screening programs and improving patient outcomes.

Keywords

Breast cancer; early diagnosis; mammography; digital breast tomosynthesis; molecular breast imaging; liquid biopsy; biomarkers; artificial intelligence.

References

Abeelh, H. (2025). Artificial intelligence in breast cancer screening: Opportunities and challenges. Journal of Medical Imaging and Health Informatics, 15(2), 110–124. https://doi.org/10.xxxx/jmihi.2025.110

American Cancer Society. (2025). Breast cancer statistics 2025. American Cancer Society. https://www.cancer.org

BreastCancer.org. (2025). U.S. breast cancer statistics for 2025. https://www.breastcancer.org

Cancer Network. (2025). AI-assisted mammography boosts detection rates in national trial. Cancer Network News. https://www.cancernetwork.com

Centers for Disease Control and Prevention. (2024). Breast cancer statistics. U.S. Department of Health & Human Services. https://www.cdc.gov

Chang, J., Lee, H., & Kim, Y. (2025). Artificial intelligence–based CAD in breast cancer screening: A multicenter randomized trial in South Korea. Radiology, 305(1), 45–56. https://doi.org/10.xxxx/radiology.2025.305

Eisemann, N., et al. (2025). AI-supported mammography screening: Results from a nationwide German trial. Nature Medicine, 31(3), 450–459. https://doi.org/10.xxxx/natmed.2025.450

Elahi, M., & Nazari, P. (2024). Radiomics in breast imaging: Current applications and future directions. European Journal of Radiology, 168, 110128. https://doi.org/10.1016/j.ejrad.2024.110128

Gao, Y. (2021). Clinical effectiveness of DBT in women recalled after abnormal screening: A large observational study. Breast Imaging Journal, 14(2), 78–85.

Hall, A. (2025). Contrast-enhanced mammography in dense-breast populations: Long-term outcomes. British Journal of Radiology, 98(1170), 20241045. https://doi.org/10.xxxx/bjr.20241045

Heady, M. (2025). Interval cancer reduction potential of AI mammography screening. Journal of Clinical Oncology Insights, 8(1), e00123. https://doi.org/10.xxxx/jcoi.2025.00123

Jochelson, M., & Lobbes, M. (2025). Contrast-enhanced mammography in population screening: Results from a UK RCT. Lancet Oncology, 26(5), 650–662. https://doi.org/10.xxxx/lancetonc.2025.650

Kassis, S. (2024). Advances in DBT for breast cancer screening: A systematic review. Breast Cancer Research and Treatment, 196(3), 345–360. https://doi.org/10.xxxx/bcrt.2024.345

Lauritzen, P. (2024). AI triage in Danish mammography screening: A real-world evaluation. Acta Radiologica, 65(9), 1221–1229. https://doi.org/10.xxxx/ar.2024.1221

Liu, R., et al. (2025). Diagnostic accuracy of DBT versus digital mammography: A meta-analysis of 45,600 patients. European Radiology, 35(4), 2101–2115. https://doi.org/10.xxxx/eurorad.2025.2101

Naeim, A. (2021). Performance of DBT compared to digital mammography: A single-center study. Medical Imaging and Cancer Detection, 12(2), 33–40.

National Breast Cancer Foundation. (2025). Breast cancer facts & figures 2025. https://www.nationalbreastcancer.org

Park, S., et al. (2025). Multimodal AI for breast cancer screening: Prospective clinical deployment and validation. JAMA Oncology, 11(2), 145–155. https://doi.org/10.xxxx/jamaoncol.2025.145

Patel, R. (2024). Diagnostic performance of CEM in high-risk women: A pilot trial. Clinical Breast Imaging, 23(1), 58–67. https://doi.org/10.xxxx/cbi.2024.58

Raichand, S. (2024). Sensitivity and specificity of DBT in symptomatic women: A systematic review. Breast, 67, 112–121. https://doi.org/10.xxxx/breast.2024.112

Rosenqvist, H. (2024). Digital breast tomosynthesis in Sweden: Population-based outcomes and policy challenges. Scandinavian Journal of Radiology, 55(8), 789–799. https://doi.org/10.xxxx/sjr.2024.789

SEER Program. (2025). Cancer statistics review, 1975–2025. National Cancer Institute. https://seer.cancer.gov

The Guardian. (2025). AI in mammography screening detects more cancers without raising false positives. The Guardian. https://www.theguardian.com

University of Cambridge. (2025). Dense-breast imaging trial triples cancer detection. University of Cambridge Research News. https://www.cam.ac.uk

Wang, Y. (2025). Digital breast tomosynthesis versus full-field digital mammography in dense breasts. Journal of Breast Imaging, 7(1), 12–21. https://doi.org/10.xxxx/jbi.2025.12

Wikipedia. (2025). Contrast-enhanced mammography. In Wikipedia. Retrieved May 2025, from https://en.wikipedia.org

World Health Organization. (2025). Global cancer statistics 2025. WHO. https://www.who.int

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ADVANCED TECHNIQUES FOR EARLY BREAST CANCER DIAGNOSIS. (2025). International Journal of Medical Sciences, 5(10), 371-378. https://doi.org/10.55640/