Articles
| Open Access |
https://doi.org/10.55640/
NUTRITION AND PHYSICAL ACTIVITY IN CONTROLLING TYPE 2 DIABETES
Uzodbekova Umidaxon Abdugopur kizi , Assistant, Department of Hospital Therapy and Endocrinology, Andijan State Medical InstituteAbstract
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia due to insulin resistance and relative insulin deficiency. The prevalence of T2DM is increasing globally, primarily due to sedentary lifestyles, poor dietary habits, and obesity. Lifestyle interventions, particularly nutrition and physical activity, play a crucial role in controlling blood glucose levels, improving insulin sensitivity, promoting weight loss, and reducing the risk of cardiovascular complications. This systematic review evaluates the effectiveness of dietary modification, physical activity, and combined interventions in adults with T2DM. Findings indicate that combined lifestyle interventions produce the most significant improvements in glycemic control (HbA1c reduction up to 1.5%), fasting blood glucose, BMI, and lipid profiles. Long-term adherence to lifestyle changes is essential for sustaining these benefits. The results emphasize the importance of individualized lifestyle strategies as a cornerstone in T2DM management, complementing pharmacological therapies.
Keywords
Type 2 diabetes mellitus, Nutrition, Physical activity, Lifestyle intervention, Glycemic control, Weight management, Metabolic health
References
American Diabetes Association. Standards of Medical Care in Diabetes—2025. Diabetes Care. 2025;48(Suppl.1):S1–S210.
Cho NH, Shaw JE, Karuranga S, et al. IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2021 and projections for 2045. Diabetes Res Clin Pract. 2022;183:109119.
International Diabetes Federation. IDF Diabetes Atlas, 10th edition. Brussels, Belgium: IDF; 2021.
DeFronzo RA. Pathogenesis of type 2 diabetes mellitus. Med Clin North Am. 2004;88(4):787–835.
Forbes JM, Cooper ME. Mechanisms of diabetic complications. Physiol Rev. 2013;93:137–188.
Uusitupa M, et al. Lifestyle interventions in the prevention of type 2 diabetes: current evidence. Curr Opin Lipidol. 2019;30(1):1–8.
Esposito K, et al. Effect of Mediterranean diet on metabolic syndrome and type 2 diabetes. Diabetes Care. 2010;33:2133–2135.
Evert AB, et al. Nutrition therapy for adults with diabetes or prediabetes: A consensus report. Diabetes Care. 2019;42:731–754.
Colberg SR, et al. Exercise and type 2 diabetes: The American College of Sports Medicine and the American Diabetes Association joint position statement. Diabetes Care. 2016;39:2065–2079.
Knowler WC, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393–403.
Pan XR, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance: The Da Qing IGT and Diabetes Study. Diabetes Care. 1997;20:537–544.
American Diabetes Association. Lifestyle management: Standards of Medical Care in Diabetes—2025. Diabetes Care. 2025;48(Suppl.1):S50–S70.
Knowler WC, Barrett-Connor E, Fowler SE, et al. Diabetes Prevention Program Research Group. N Engl J Med. 2002;346:393–403.
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