Articles
| Open Access |
https://doi.org/10.55640/
CERVICAL PATHOLOGY AND VAGINAL MICROBIOME IN INTRAUTERINE DEVICE USERS: RISKS AND OBSERVATIONS
Atakhodjaeva F.A., Tashbaeva U.I. , Associate Professor, Tashkent State Medical University, Tashkent, Uzbekistan, Master’s degree, Tashkent State Medical UniversityAbstract
This article studies the correlation between the prolonged use of intrauterine contraceptive devices (IUDs) and the development of cervical pathology. A comparative analysis of clinical, cytological, colposcopic, and microbiological data was conducted in women with and without IUDs. A higher incidence of inflammatory changes and low-grade cervical intraepithelial neoplasia (CIN 1) was revealed among IUD users.
Keywords
Intrauterine device, cervix, dysplasia, CIN 1, inflammation, HPV, colposcopy, cytology.
References
International Agency for Research on Cancer. Cervical Cancer. Global Cancer Observatory. 2022. https://www.iarc.who.int/cancer-type/cervical-cancer
Bosch FX, Lorincz A, Muñoz N, Meijer CJ, Shah KV. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol. 2002;55(4):244-265. doi:10.1136/jcp.55.4.244
Schiffman M, Wentzensen N. From human papillomavirus to cervical cancer. Obstet Gynecol. 2010;116(1):177–185. doi:10.1097/AOG.0b013e3181eeb2a9
United Nations, Department of Economic and Social Affairs, Population Division. World Contraceptive Use 2023. https://www.un.org/development/desa/pd/data/world-contraceptive-use
Skorstengaard M, Lynge E, Napolitano G, et al. Risk of precancerous cervical lesions in women using a hormone-containing intrauterine device and other contraceptives: a register-based cohort study from Denmark. Hum Reprod. 2021;36(7):1796–1807. doi:10.1093/humrep/deab104
Kim K, Park H, Kim H, et al. Association of intrauterine device use with risk of cervical intraepithelial neoplasia and HPV infection: a nationwide cohort study. Sci Rep. 2021;11:21599. doi:10.1038/s41598-021-01086-6
Castellsagué X, Díaz M, Vaccarella S, et al. Intrauterine device use, cervical infection with human papillomavirus, and risk of cervical cancer: a pooled analysis of 26 epidemiological studies. Lancet Oncol. 2011;12(11):1023–1031. doi:10.1016/S1470-2045(11)70223-6
Solomon D, Nayar R. The Bethesda System for Reporting Cervical Cytology: Definitions, Criteria, and Explanatory Notes. 3rd ed. Springer; 2015.
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