Articles
| Open Access |
https://doi.org/10.55640/
2-AMINO-6-OXYPURINE AS A KEY SCAFFOLD FOR THE DESIGN OF BIOACTIVE HYDRAZONE COMPOUNDS
Giyasov Kuchkar , Tashkent state agrarian university, UzbekistanAbstract
This scientific research explored the synthesis and technological aspects of
bioactive hydrazone compounds formed through the reactions between 2-amino-6-oxypurine and hydrazine. The ideal reaction conditions, such as temperature, duration, solvent, and pH, were identified, and the structures of the obtained products were verified through IR and TLC analysis. The synthesized hydrazones demonstrated significant biological activity, suggesting their potential use as pharmaceutical and agrochemical agents. A technological scheme for the synthesis process was developed based on the results, featuring thoroughly justified selectivity, yield, and purification steps.
Keywords
2-Amino-6-oxypurine, guanine, hydrazine, hydrazones, nucleophilic reactions, electrophilic reactions, synthesis, IR spectroscopy, thin-layer chromatography, biological activity, pharmaceutical applications, agrochemicals.
References
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