This article analyzes the morphological, immunological, and histopathological features of tuberculosis detected at a late stage in patients with acquired immunodeficiency. The research was conducted under the conditions of Uzbekistan, particularly in the Fergana region, and revealed that in cases of delayed diagnosis, granulomatous reactions are weakened, caseous necrosis predominates, and distinctive morphological differences are linked to immunohistochemical markers. The findings provide a significant scientific basis for improving early detection strategies for tuberculosis in immunodeficient individuals.

tuberculosis, immunodeficiency, morphology, immunohistochemistry, granuloma, HIV.

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