Determination of biochemical processes, endogenous intoxication and histomorphological and planimetric indicators in purulent-necrotic lesions of the foot in an experimental way  and in patients with purulent-necrotic processes in diabetes mellitus, the condition of the IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, TNF-α, and INF-γ system based on the dynamics of cytokine levels was studied. Complex surgical treatment of the drug Reomannisol corrects the balance of cytokines, allowing them to have an antioxidant effect on the cytokine system.

diabetic purulent-necrotic foot model, cytokine system, complex treatment, Reomannisol, Reosorbylact.

Yusufjanovich, E. U., Rafiqovich, Z. A., & Irsalievich, E. K. (2023). Assessment of the Process of Epithelialization After Complex Treatment of Diabetic Foot Syndrome. Texas Journal of Medical Science, 16, 19-23.

Yusufjanovich, E. U., & Rafiqovich, Z. A. (2023). Treatment of purulent-necrotic lesions of the lower extremities with modern drugs. Conferencea, 88-94.

Зохиров, А. Р., Абдусаломов, Б. А., & Моминов, А. Т. (2022). Совершенствование комплексного лечения с учетом патофизиологических изменений гнойно-некротических поражений нижних конечностей при сахарном диабете.

Ergashev, U. Y., Zokhirov, A. R., & Ernazarov, K. I. (2022). THE STUDY OF PATHOMORPHOLOGICAL DIAGNOSIS OF VITAL ORGANS AFTER MODERN TREATMENT OF DIABETIC FOOT SYNDROME.

Эргашев, У. Ю., & Зохиров, А. Р. (2023). Оценка эффективности малоинвазивных операций при механической желтухе и применение алгоритма. European Journal of Interdisciplinary Research and Development, 12, 6-16.

Эргашев, У. Ю., & Зохиров, А. Р. (2023). ИЗУЧЕНИЕ ПАТОМОРФОЛОГИИ ПЕЧЕНИ ПРИ ЭКСПЕРИМЕНТАЛЬНОМ СИНДРОМЕ ДИАБЕТИЧЕСКОЙ СТОПЫ. European Journal of Interdisciplinary Research and Development, 12, 27-31.

Yusufjanovich, E. U., Irisbaevich, M. G., Rafiqovich, Z. A., & Irsaliyevich, E. K. (2023). Evaluation of Effectiveness of Splenectomy in Chronic Leukemias. World Bulletin of Public Health, 19, 79-83.

Yusufjanovich, E. U., Rafiqovich, Z. A., & Tohirovich, G. B. (2023). PRINCIPLES OF STUDYING LIVER MORPHOLOGY IN EXPERIMENTAL DIABETIC FOOT SYNDROME. World Bulletin of Public Health, 19, 63-65.

Ergashev, U. Y., Minavarkhujayev, R. R., Gafurov, B. T., Malikov, N. M., Ortiqboyev, F. D., & Abdusalomov, B. A. (2022). Efficiency of Percutaneous Minimally Invasive Technologies in the Treatment of Patients with Obstructive Jaundice.

Моминов, А. Т., Маликов, Н. М., Якубов, Д. Р., & Абдусаломов, Б. А. (2022). Проблемы обезболивания в амбулаторной хирургии. European Journal of Interdisciplinary Research and Development, 10, 81-89.

Ergashev, U. Y., Abdusalomov, B. A., Minavarkhojayev, R. R., Ortiqboyev, F. D., & Malikov, N. M. (2023). Evaluation of the pathomorphology of regeneration in diabetic foot syndrome and determination of its dependence on biochemical processes. World Bulletin of Public Health, 19, 66-78.

Abdusalomov, B. A., & Rafiqovich, Z. A. (2023). THE MECHANISM OF ACTION OF THE GEL FORM OF COLLAGEN IN DIABETIC WOUNDS. International Journal of Medical Sciences And Clinical Research, 3(03), 96-103.

Ergashev, U. Y., Malikov, N. M., Yakubov, D. R., Abdusalomov, B. A., & Gafurov, B. T. (2023). Use of Collagen and Fibroblasts in Modern Medicine. Eurasian Research Bulletin, 17, 78-84.

Ergashev, U. Y., Mominov, A. T., Malikov, N. M., Yakubov, D. R., & Abdusalomov, B. A. (2023). MODERN APPROACH TO COMPLEX TREATMENT OF DIABETIC FOOT ULCERS. LITERATURE REVIEW.

Ergashev, U. Y., Abdusalomov, B. A., & Zohirov, A. R. (2023, May). Eksperimental diabetik tavon sindromida hayotiy muhim a’zolarning morfologik o’zgarishlarini nazorat qilish. /Material of International scientific and practical conference" An integrated approach to the treatment of complications of diabetes".

Abdusalomov, B. A. (2023). USE OF MODERN METHODS IN THE TREATMENT OF CHRONIC WOUNDS. Journal of Academic Research and Trends in Educational Sciences, 2(3), 213-220.

Abdusalomov, B. A. (2023). The Role of Collagen in The Mechanisms of Chronic Wound Healing for Diabetic Foot Syndrome. Texas Journal of Medical Science, 26, 86-94.

Ergashev, U. Y., Mominov, A. T., Malikov, N. M., Yakubov, D. R., & Abdusalomov, B. A. (2023). MODERN APPROACH TO COMPLEX TREATMENT OF DIABETIC FOOT ULCERS.(LITERATURE REVIEW).

Эргашев, У. Ю., Зохиров, А. Р., Минавархужаев, Р. Р., Абдусаломов, Б. А., & Ортикбоев, Ф. Д. (2023). Оценка эффективности малоинвазивных операций при механической желтухе и применение алгоритма. European Journal of Interdisciplinary Research and Development, 12, 6-16.

Ergashev, U., Malikov, N., Yakubov, D., Abdusalomov, B., & Gafurov, B. (2023). Use of Collagen and Fibroblasts in Modern Medicine. Eurasian Res. Bull, 17, 78-84.

Зохиров, А. Р., Абдусаломов, Б. А., & Моминов, А. Т. (2022). Совершенствование комплексного лечения с учетом патофизиологических изменений гнойно-некротических поражений нижних конечностей при сахарном диабете.