The second stage of the study involved evaluating the effect of tiotriazoline on radiological dynamics and reparative processes in lung tissue among patients with MDR-TB. A total of 142 patients were included, of whom 81 received tiotriazoline in addition to standard chemotherapy. The assessment included the rate of infiltrate resolution, cavity closure, the need for surgical intervention, and morphological characteristics of granulomas. The use of tiotriazoline resulted in faster healing of infiltrative lesions, a significantly higher rate of cavity closure, and a marked reduction in the need for surgical procedures. Morphological analysis confirmed accelerated formation of a connective tissue capsule and limitation of specific inflammation.

tuberculosis, MDR-TB, tiotriazoline, radiology, pulmonary cavity, repair, granuloma.

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