Tuberculosis remains the second leading cause of infectious mortality after COVID-19. In 2022, a total of 10.6 million cases and 1.3 million deaths were registered worldwide. Multidrug-resistant tuberculosis (MDR-TB) poses a serious threat due to the high prevalence of resistance among Mycobacterium tuberculosis strains. The aim of this study was to assess the frequency, demographic characteristics, and major clinical features of MDR-TB among patients in the Bukhara and Navoi regions of the Republic of Uzbekistan.

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