Childhood obesity is a major public health concern associated with the early development of metabolic syndrome (MetS), a cluster of risk factors including insulin resistance, dyslipidemia, hypertension, and central adiposity. This study aimed to examine the impact of obesity on MetS development in a pediatric population by evaluating anthropometric measurements, biochemical markers, and early indicators of metabolic and cardiovascular dysfunction. A cross-sectional analysis was conducted on 150 children aged 8–16 years, categorized as normal-weight, overweight, or obese. Anthropometric parameters, fasting glucose and insulin levels, lipid profiles, and blood pressure were assessed. Insulin resistance was calculated using the HOMA-IR index. Results demonstrated that obese children exhibited significantly higher BMI, waist circumference, blood pressure, triglycerides, LDL cholesterol, and HOMA-IR, with lower HDL cholesterol compared to normal-weight peers (p < 0.05). The prevalence of MetS was markedly higher in the obese group (36%). These findings indicate that childhood obesity is strongly associated with the early onset of metabolic syndrome and highlight the importance of early screening and intervention strategies to prevent long-term cardiometabolic complications.

Childhood obesity, Metabolic syndrome, Insulin resistance, Dyslipidemia, Pediatric health, Cardiometabolic risk

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