Chronic obstructive pulmonary disease (COPD) remains a focus of medical science and practice. This article presents a review of the current literature on COPD in women. It presents data on the prevalence of the disease, specific susceptibility to risk factors, age-related aspects of development, progression, outcomes, and clinical manifestations of COPD, as well as differences in response to pharmacotherapy in women and men. Thus, a number of studies have demonstrated a high susceptibility of women to the effects of tobacco smoke, a predisposition to the development of the bronchitis phenotype of COPD, a severe course with frequent exacerbations, and a low risk of death after exacerbations. The results of this review suggest that gender differences can be explained by anatomical differences in the development of the respiratory system and the cyclical hormonal activity of the female body, which manifests itself in greater airway hyperreactivity and, consequently, a higher incidence of severe COPD.

chronic obstructive pulmonary disease, women.

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