Articles | Open Access | https://doi.org/10.55640/

METABOLIC SYNDROME: PATHOGENESIS, CLINICAL SIGNIFICANCE AND PREVENTIVE APPROACHES

Mavlonov Namoz Halimovich , Associate Professor, PhD, Department of Internal Diseases in Family Medicine, Bukhara State Medical Institute

Abstract

Metabolic syndrome (MS) is a complex set of pathophysiological conditions characterized by abdominal obesity, insulin resistance, arterial hypertension, dyslipidemia, and disorders of carbohydrate metabolism. In recent years, the prevalence of MS has been sharply increasing both worldwide and among the population of Uzbekistan. The clinical importance of this condition lies in the fact that it is a strong independent risk factor for cardiovascular diseases, type 2 diabetes mellitus, atherosclerosis, and myocardial infarction.
Genetic predisposition, unhealthy diet, insufficient physical activity, stress, and hormonal imbalances play leading roles in the development of MS. Early detection and comprehensive preventive strategies are essential for reducing the burden of cardiovascular diseases.

Keywords

abdominal obesity, cardiovascular diseases, atherosclerosis, diabetes mellitus.

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METABOLIC SYNDROME: PATHOGENESIS, CLINICAL SIGNIFICANCE AND PREVENTIVE APPROACHES. (2025). International Journal of Medical Sciences, 5(12), 381-383. https://doi.org/10.55640/