The study was conducted in patients with malignant tumors of the epigastric region, and the prevalence of personality changes includes information on the characteristics, principles of adaptation, structural features and comorbidity. Personality changes in patients with malignant tumors of the epigastric region are determined by the character and characteristics of each person, the severity of the disease, typological characteristics, the prevalence of psychopathological symptoms characteristic of the disease, polymorphism, and clinical examples of patients with schizotypal, hysterical and paranoid disorders are presented. When comparing the prevalence of personality changes, explanations are given about the differences between paranoid, schizotypal, and phobias in patients with gastroesophageal reflux, gastric and duodenal malignant tumors, and irritable bowel syndrome.

personality changes, gastric and duodenal malignant tumor pathology, affective disorders, gastroesophageal reflux.

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