This study evaluates the morphological and morphometric characteristics of the stenotic area in pyloroduodenal stenosis according to disease stages. The study included 54 patients, with biopsy samples obtained exclusively from the ulcer-scarred pyloroduodenal region at five points per patient. The specimens were analyzed at the levels of the mucosal, submucosal, and upper muscular layers. The results demonstrated progressive mucosal thinning, reduction of glandular volume, and intensification of inflammatory and fibrotic changes with advancing stages of pyloroduodenal stenosis.

pyloroduodenal stenosis, morphological analysis, morphometry, fibrosis, mucosa.

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