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https://doi.org/10.55640/
THE SIGNIFICANCE OF IMMUNOPATHOLOGY IN THE ORIGIN OF TUMOR CELLS AND THE MOLECULAR MECHANISMS OF OPPORTUNISTIC INFECTION CONTROL IN IMMUNODEFICIENCY
Ergasheva Sevinch Khayrullayevna,Kholmurodov Asqar Bekmurodovich , Karshi State University, Faculty of Medicine Student of the General Medicine Program, Group 024-71 “B”,Karshi State University, Faculty of Medicine Lecturer, Faculty of MedicineAbstract
This article discusses the concept of immunopathology, its role in the development of neoplastic (tumor) cells, as well as the mechanisms of development and regulation of opportunistic infections in conditions of immunodeficiency. The study reveals the molecular basis of pathological processes arising as a result of immune system dysfunction.
Keywords
Immunopathology, immune system, autoimmune reactions, immunodeficiency, tumor cells, immune surveillance, T-lymphocytes, NK cells, PD-1/PD-L1 pathway, MHC molecules, Treg cells, apoptosis.
References
Abbas A.K., Lichtman A.H. Cellular and Molecular Immunology. 10th ed. Elsevier, 2022.
Janeway C.A. et al. Immunobiology. 9th ed. Garland Science, 2021.
Ahmedov M.M. Fundamentals of Immunology and Immunopathology. Tashkent, 2019.
Roitt I.M. et al. Immunology. 9th ed. Elsevier, 2020.
Kumar V. et al. Robbins & Cotran Pathologic Basis of Disease. 10th ed. Elsevier, 2021.
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