Diffuse toxic goiter (DTG), also known as Graves’ disease, is an autoimmune disorder of the thyroid gland characterized by diffuse enlargement of the gland and excessive production of thyroid hormones. This condition leads to thyrotoxicosis, which affects multiple organs and systems. DTG predominantly occurs in women of working age and has a strong genetic and immunological background. The present article reviews the etiology, pathogenesis, clinical features, ophthalmopathy, systemic involvement, and severity classification of diffuse toxic goiter.

diffuse toxic goiter, Graves’ disease, thyrotoxicosis, autoimmune thyroid disease, ophthalmopathyIntroduction

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