Chronic pharyngitis is a common inflammatory condition of the pharyngeal mucosa in children, often resulting in discomfort, recurrent infections, and impaired quality of life. Early diagnosis and comprehensive management are essential to reduce symptoms and prevent recurrence. This study aimed to optimize the diagnosis and comprehensive treatment of chronic pharyngitis in children and evaluate the effectiveness of multi-targeted therapeutic strategies. A prospective clinical study was conducted involving 120 children aged 5–14 years diagnosed with chronic pharyngitis. Comprehensive evaluation included clinical history, pharyngoscopy, laboratory investigations, and assessment of contributing factors. Patients received a comprehensive treatment protocol consisting of local anti-inflammatory therapy, antiseptics, immunomodulators, physiotherapy, and management of comorbid conditions. Follow-up assessments were conducted at 1, 3, and 6 months to evaluate symptom resolution, pharyngoscopic findings, and recurrence rates. The study included 68 boys (56.7%) and 52 girls (43.3%) with a mean age of 9.2 ± 2.8 years. Common symptoms were sore throat (100%), dryness (85%), foreign body sensation (63%), cough (47%), and voice changes (32%). Pharyngoscopy revealed mild, moderate, and severe inflammation in 40%, 45%, and 15% of patients, respectively. Comorbidities were present in 58%, mainly allergic rhinitis and adenoid hypertrophy. Six-month follow-up showed complete resolution in 70% of patients, partial improvement in 22%, persistent symptoms in 8%, and recurrence in 10%. Comprehensive treatment was effective in improving clinical outcomes, particularly when adherence and management of comorbidities were ensured. Early and accurate diagnosis combined with a multi-targeted, individualized treatment approach significantly improves clinical outcomes in children with chronic pharyngitis and reduces recurrence. Attention to comorbid conditions and caregiver education is essential for sustained therapeutic success.

Chronic pharyngitis; Children; Diagnosis; Comprehensive treatment; Pediatric otorhinolaryngology; Recurrence; Pharyngoscopy; Immunomodulation

Bluestone CD, Stool SE, Kenna MA. Pediatric Otolaryngology. 5th ed. Philadelphia: Elsevier; 2014. p. 112–118.

Gates GA, Bluestone CD. Chronic Pharyngitis in Children: Clinical and Epidemiological Aspects. Laryngoscope. 2012;122(7):1451–1457.

Snow JB, Wackym PA. Ballenger’s Otorhinolaryngology: Head and Neck Surgery. 18th ed. Shelton: People’s Medical Publishing; 2016. p. 220–226.

Dhingra PL, Dhingra S. Diseases of the Throat and Pharynx in Children. J Pediatr Otorhinolaryngol. 2013;77(6):823–829.

Coticchia JM, Zacharek MA, Patel RG. Clinical Pharyngoscopy and Assessment of Pediatric Pharyngeal Inflammation. Int J Pediatr Otorhinolaryngol. 2010;74(9):1007–1012.

Krouse JH. Allergic Rhinitis and Its Role in Chronic Pharyngitis in Children. Otolaryngol Clin North Am. 2011;44(3):649–659.

Brook I. Microbiology and Management of Chronic Pharyngitis in Pediatric Patients. Pediatr Infect Dis J. 2010;29(8):752–757.

Schaefer SD. Immunologic Considerations in Pediatric Pharyngeal Disorders. Laryngoscope. 2011;121(4):789–794.

Valtonen H, et al. Environmental Factors Influencing Upper Respiratory Tract Infections in Children. Pediatr Allergy Immunol. 2012;23(2):150–156.

Stucken EZ, et al. Comprehensive Management of Chronic Pharyngitis in Children. Int J Pediatr Otorhinolaryngol. 2014;78(12):2090–2095.

Roland PS, et al. Evidence-Based Guidelines for the Treatment of Pediatric Chronic Pharyngitis. Otolaryngol Head Neck Surg. 2013;149(1):1–12.

Brook I, Foote PA. Recurrence of Chronic Pharyngitis in Children: Role of Allergies and Compliance. Clin Pediatr (Phila). 2015;54(3):225–230.