Articles | Open Access | https://doi.org/10.55640/

CRANIOSYNOSTOSIS: TRIGONOCEPHALY. THE ROLE OF MULTISLICE COMPUTED TOMOGRAPHY IN THE DIAGNOSIS OF TRIGONOCEPHALY AND THE ANALYSIS OF ORBITAL CHANGES BEFORE AND AFTER RECONSTRUCTIVE SURGERY

Soibov Suratjon , Republican Scientific Center of Neurosurgery Tashkent, Uzbekistan, Alfraganus University
Ashrapov Jamshid , Republican Scientific Center of Neurosurgery Tashkent, Uzbekistan, Alfraganus University

Abstract

Craniosynostosis is the pathological premature closure of cranial sutures, leading to skull deformity and impaired normal brain growth. This study focuses on the diagnosis and treatment of one of its forms — trigonocephaly, which results from early fusion of the metopic suture. We conducted an analysis of morphological changes in the orbital region before and after fronto-orbital advancement. It was demonstrated that reconstructive surgery restores the anatomical proportions of the orbits and provides a pronounced aesthetic improvement. The obtained data confirm the high diagnostic value of multislice computed tomography (MSCT) as a method for diagnosing and objectively assessing the outcomes of surgical treatment of trigonocephaly.

Keywords

craniosynostosis, trigonocephaly, metopic suture, multislice computed tomography, reconstructive surgery, pediatric neurosurgery.

References

Wilkie A. O. M., Morriss-Kay G. M. Genetics of craniofacial development and malformation. Nat Rev Genet. 2023.

Elahi E. et al. FGFR2 and TWIST1 mutations in craniosynostosis syndromes. Am J Med Genet. 2022.

Twigg S. R. F. et al. Mutations in EFNB1 and craniofacial development. Nat Genet. 2021.

Rinaudo F. A. et al. Environmental and mechanical factors influencing cranial suture fusion. Front Mol Biosci. 2022.

Aldridge K. et al. Brain growth and cranial suture development: interaction and timing. Dev Dyn. 2023.

Bloch K. et al. New diagnostic criteria for metopic ridges and trigonocephaly. Orphanet J Rare Dis. 2024.

Rinaudo F.A., Bloch K. et al. Fronto-orbital remodeling outcomes in metopic craniosynostosis: a multicenter review. Childs Nerv Syst. 2022.

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CRANIOSYNOSTOSIS: TRIGONOCEPHALY. THE ROLE OF MULTISLICE COMPUTED TOMOGRAPHY IN THE DIAGNOSIS OF TRIGONOCEPHALY AND THE ANALYSIS OF ORBITAL CHANGES BEFORE AND AFTER RECONSTRUCTIVE SURGERY. (2025). International Journal of Medical Sciences, 5(12), 683-687. https://doi.org/10.55640/