This article is devoted to the study of the ability of Proteus vulgaris bacteria to cause infections in children and its resistance to antibiotics. In the study, the antibiotic susceptibility of Proteus vulgaris strains isolated from pediatric patients was analyzed using clinical laboratory methods. In addition, severe infectious complications caused by the bacterium, including uropathies, sepsis, and gastroenterological diseases, were observed. The results indicate that Proteus vulgaris is resistant to certain antibiotics and can cause severe and complex infectious complications in children, which provides important information for infection prevention and the development of effective treatment strategies.

Proteus vulgaris, children, antibiotic resistance, infection, severe complications, clinical microbiology.

Office of the President of the Republic of Uzbekistan. (2018, December 7). Decree on Comprehensive Measures to Fundamentally Improve the Healthcare System of the Republic of Uzbekistan (Decree No. PF-5590).

Hauser, G. (1885). Beiträge zur Kenntnis der Bakterienflora des verdorbenen Fleisches. Leipzig: Engelmann.

Jorgensen, J. H., & Ferraro, M. J. (2009). Antimicrobial susceptibility testing: General principles and contemporary practices. Clinical Infectious Diseases, 49(11), 1749–1755.

Mobley, H. L. T., & Warren, J. W. (1990–2020). Pathogenesis of urinary tract infections caused by Proteus species. Microbiology and Molecular Biology Reviews, 54(4), 625–636.

Safarov, R. S., & Tursunov, B. K. (2018). Antibiotic susceptibility of Proteus vulgaris in children. Uzbekistan Journal of Pediatrics, 3(2), 45–52.

Karimov, A. A., & Yusupov, S. A. (2020). Diagnosis and treatment of infections associated with Proteus vulgaris. Scientific Bulletin of Tashkent Medical Academy, 5(1), 12–18.

Clinical and Laboratory Standards Institute (CLSI). (2021). Performance Standards for Antimicrobial Susceptibility Testing (31st ed.). Wayne, PA: CLSI.

Forbes, B. A., Sahm, D. F., & Weissfeld, A. S. (2007). Bailey & Scott’s Diagnostic Microbiology (12th ed.). St. Louis, MO: Mosby.

Todar, K. (2020). Todar’s Online Textbook of Bacteriology.

Yusupova, D. K., & Rasulov, M. R. (2019). Analysis of bacterial uropathies and antibiotic resistance. Uzbekistan Journal of Microbiology, 4(3), 23–30