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| Open Access |
https://doi.org/10.55640/
SCARLET FEVER IN YOUNG CHILDREN AND ITS DISTINCTIVE CLINICAL COURSE
Ulugov Shuhrat Jabborovich , Asia International University, Bukhara, UzbekistanAbstract
Scarlet fever is an acute infectious disease caused by Group A β-hemolytic streptococcus (Streptococcus pyogenes), predominantly affecting children. This scientific article provides a comprehensive analysis of the epidemiology, etiology, pathogenesis, immune and inflammatory mechanisms, morphological and histopathological changes, clinical manifestations, diagnostic approaches, treatment strategies, and preventive measures of scarlet fever in young children. Particular attention is paid to age-related characteristics of the disease course, which are associated with the immaturity of the immune system. The importance of early diagnosis and timely antibiotic therapy in preventing severe complications is emphasized based on current scientific literature.
Keywords
scarlet fever, Streptococcus pyogenes, young children, erythrogenic toxin, superantigen, immune response, antibiotic therapy.
References
Nelson W.E. Nelson Textbook of Pediatrics. 21st ed. Elsevier; 2020.
Murray P.R., Rosenthal K.S. Medical Microbiology. 9th ed. Elsevier; 2020.
World Health Organization. Scarlet fever: clinical guidelines.
Centers for Disease Control and Prevention (CDC). Group A Streptococcal Infections.
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This work is licensed under a Creative Commons Attribution 4.0 International License.