Articles | Open Access | https://doi.org/10.55640/

FEATURES OF THE FUNCTIONAL STATE OF THE CENTRAL NERVOUS SYSTEM IN CHILDREN WITH POST-TRAUMATIC ENCEPHALOPATHY

Nasirova Dilfuza Shavkatovna , Tashkent State Medical University

Abstract

 Post-traumatic encephalopathy (PTE) in children is a common and poorly understood consequence of mild to moderate traumatic brain injury (TBI). Despite the subtle clinical manifestations in the acute phase, persistent cognitive, autonomic, and neurophysiological impairments can develop in the late phase of PTE.

This study presents data from a comprehensive clinical, neurological, neuropsychological, and instrumental examination of 46 children aged 7 to 18 years who had suffered a concussion (Group A, n=20) or brain contusion (Group B, n=26). An analysis of complaints, headache severity using the Visual Analog Scale (VAS), clinical neurostatus, and the functional state of the autonomic nervous system (Guillaume-Vein scale), as well as EEG and MRI results, was conducted. The primary complaint in most children was tension-type headache of moderate intensity.

Keywords

x

References

Abdullaev D. D., Tozhiev M. T., et al. Features of the clinical course and diagnosis of acute traumatic brain injury in children // Bulletin of emergency medicine. - Tashkent, 2014. - N2. - P. 35-36.

Artaryan A. A., Iova A. S., Garmashov Yu. A., Banin A. V. Traumatic brain injury in children // Traumatic brain injury: clinical guidelines / edited by A. N. Konovalov, L. B. Likhterman, A. A. Potapov. Moscow: Antidor, 2001. Vol. 2. P. 603–648.

Asilbekov U. E. Clinical presentation, diagnosis, and outcomes of severe traumatic brain injury in children of different age groups // Neurosurgery and neurology of Kazakhstan. 2012. No. 1 (26). P. 12–16.

Bogolepova A. N., Chukanova E. I. The problem of neuroplasticity in neurology. S. S. Korsakov Journal of Neurology and Psychiatry. 2010; 110 (8): 62–65.

Vizilo, T. L. Traumatic encephalopathy: clinical presentation and treatment / T. L. Vizilo, I. V. Vlasova, E. N. Kharkova. // Attending physician. - 2016. - No. 5. - P. 28–32

Vorobyova O. V., Vein A. M. Post-traumatic headaches. Consilium medicum. 1999; 1 (2): 73–75.

Glushchenko V. V., Shabanov P. D. Minimal brain dysfunction. Moscow: Binom; 2013.

Goryunova A. V. Post-traumatic headache in children. Korsakov Journal of Neurology and Psychiatry. 2009; 109 (12): 55-59.

Zavadenko N. N., Guzilova L. S., Iznak A. F., Iznak E. V. Consequences of severe traumatic brain injury in adolescents: features of clinical manifestations and treatment. Issues of modern pediatrics. 2010; 9 (4): 57-67.

Zavadenko N. N., Kemalov A. I. Consequences of severe traumatic brain injury in children and their treatment. Issues of modern pediatrics. 2006;5(4):14-21.

Zavadenko N.N., Nemkova S.A. Developmental Disorders and Cognitive Dysfunctions in Children with Nervous System Diseases. Scientific and Practical Guide. Moscow: MK; 2016.

Kemalov A.I. Brain Dysfunctions in the Late Period of Severe Closed Traumatic Brain Injury in Children: Diss. ... Cand. Sci. (Med.)]. Moscow, 2006.

Likhterman L.B. Traumatic Brain Injury. Diagnostics and Treatment. Moscow: GEOTAR-Media; 2014. (In Russ.)].

14. Myakotnykh V.S., Talankina N.Z., Borovkova T.A. Clinical, pathophysiological, and morphological aspects of the late period of closed traumatic brain injury. S.S. Korsakov Journal of Neurology and Psychiatry. 2002;102(4):61-65.

Ovsyannikov D.M., Chekhonatsky A.A., Kolesov V.N., Bubashvili A.I. Social and epidemiological aspects of traumatic brain injury (review) // Saratov Journal of Medical Scientific Research. 2012. Vol. 8, No. 3. Pp. 777–785.

Petrukhin A.S. Childhood Neurology. Moscow, Meditsina, 2004. — 783 p.

Talypov A.E., Myatchin M.Yu., Kuksova N.S., Ioffe Yu.S., Kordonskiy A.Yu. Drug-induced neuroprotection in the acute period of moderate traumatic brain injury. Medical Council. 2015;10:82-92.

Shalkevich L.V., Lvova O.A., Kulagin A.E., Talabaev M.V., Ivashina E.N., Sulimov A.V. Clinical guidelines for the diagnosis and treatment of traumatic brain injury in children, principles of clinical examination. Pediatric Neurology, issue 3: clinical guidelines / edited by V.I. Guzeva. Moscow: MK, 2015. pp. 147–174.

Akhtar JI. Digital decoding of pediatric traumatic brain injury. Crit Care Med. 2015;43(3):722-723. doi:10.1097/CCM.0000000000000799

Anderson V, Yeates KO. Pediatric Traumatic Brain Injury. Cambridge University Press; 2010.

Dennis EL, Baron D, Bartnik-Olson B, et al. ENIGMA brain injury: Framework, challenges, and opportunities. Hum Brain Mapp. 2022;43(1):149-166. doi:10.1002/hbm.25046

Griffin, A., Deeba, F., Dennison, T., & Moore, A. (2020). Perspectives on neuropsychology and clinical care in paediatric and adolescent medicine. Clinical Child Psychology and Psychiatry, 25(3), 687-697. https://doi.org/10.1177/1359104520915249

Huie JR, Mondello S, Lindsell CJ, et al. Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations. J Neurotrauma. 2021;38(18):2514-2529. doi:10.1089/neu.2019.6762

Middleton JA. Practitioner review: Psychological sequelae of head injury in children and adolescents. J Child Psychol Psychiat. 2001;42(2):165-180.

Shaw L, Morozova M, Abu-Arafeh I. Chronic post-traumatic headache in children and adolescents: systematic review of prevalence and headache features. Pain Manag. 2018;8(1):57-64.

Article Statistics

Downloads

Download data is not yet available.

Copyright License

Download Citations

How to Cite

FEATURES OF THE FUNCTIONAL STATE OF THE CENTRAL NERVOUS SYSTEM IN CHILDREN WITH POST-TRAUMATIC ENCEPHALOPATHY. (2025). International Journal of Medical Sciences, 5(12), 1164-1173. https://doi.org/10.55640/