The pathomorphological structure of polyp tissues was analyzed in 90 patients with chronic polypous rhinosinusitis. The study focused on determining the structure of the integumental epithelium and membrane, cellular composition, polyp and glandular stroma composition, activation, and infiltration.  In 26 (28.9%) patients, respiratory epithelium was most frequently identified as the main component of the polyp tissue. Goblet cell hyperplasia and desquamation were observed. In most cases, 60 (66.7%) polyp tissues showed multiple glands. The structural analysis of the obtained micropreparations revealed "young" forms of polyps in 68 (75.6%) patients, while the fibro-inflammatory type was observed in 23 (25.5%) cases. Important indicators of polyp recurrence were identified: significant thickening of the basal layer and membranes, activated eosinophilia, signs of integumental epithelium proliferation, increased sclerosis, and low stromal infiltration.

polyp, morphology, tissue, rhinosinusitis

Djuraev J.A., Soatov I.O. MET (Tyrosine kinase receptor gene) Gene polymorphism among patients with chronic polyposis rhinosinusitis and chronic rhinosinusitis. Clinical Medicine, Tashkent Medical Academy Journal, 2023, No. 1, pp. 113-116. ISSN 2181-7812. Tashkent Medical Academy, Tashkent, Uzbekistan.

Djuraev J.A., Soatov I.O., Rakhimjanova G.A., Mardonov Kh.A. Results of clinical-cytomorphological research conducted to identify various forms of chronic polypoid rhinosinusitis. Eurasian Journal of Otorhinolaryngology - Head and Neck Surgery, 2024, Vol. 3, Issue 4, pp. 56-61. Tashkent Medical Academy, Tashkent, Uzbekistan. DOI: https://doi.org/10.57231/j.ejohns.2024.3.4.0010

Juraev Jamolbek Abduqahhorovich, Soatov Ilyosjon Olim ugli. Comparative analysis of the rs3918242 MMP9 gene polymorphism frequency in patients with chronic polypoid rhinosinusitis. Problems of Biology and Medicine, 2024, No. 4 (155), pp. 73-76. Tashkent Medical Academy, Tashkent, Uzbekistan. ISSN 2181-7812.

Soatov Ilyosjon Olim ugli, Djuraev Jamolbek Abdukakharovich. Pathomorphological structure of polypous tissue in patients with chronic polypous rhinosinusitis. Uzbekistan Medical Journal, 2023, Issue 2. pp. 59-64. Tashkent Medical Academy, Tashkent, Uzbekistan.

Soatov Ilyosjon Olim ugli. Biomarkers and genotyping in the development of chronic polypous rhinosinusitis. Association of Pulmonologists of Central Asia, 2024, pp. 100-103. Tashkent Medical Academy, Tashkent, Uzbekistan. ISSN: - (Article published in the Bulletin of the Pulmonology Center, https://tbcenter.uz/)

Khasanov U.S., Djuraev J.A., Mardonov Kh.A., Soatov I.O., Khodjaeva D.M., Khakimov R.A. Results of comparative analysis of TLR4 gene rs4986791 polymorphism in the development of nasopharyngeal tonsil hypertrophy. Eurasian Journal of Otorhinolaryngology - Head and Neck Surgery, 2024, Vol. 3, Issue 4, pp. 23-27. Tashkent Medical Academy, Tashkent, Uzbekistan. DOI: https://doi.org/10.57231/j.ejohns.2024.3.4.004

Khasanov U.S., Djuraev J.A., Mardonov Kh.A., Soatov I.O., Khodjaeva D.M., Khakimov R.A. Results of the analysis of MBL2 gene polymorphism in alleles and genotypes during the development of nasopharyngeal tonsillitis. Eurasian Journal of Otorhinolaryngology - Head and Neck Surgery, 2024, Vol. 3, Issue 4, pp. 17-22.

Khasanov U.S., Soatov I.O., Khodjanov S.Kh., Akhundjanov N.O., Rakhimjanova G.A. Results of the analysis of rs20417 polymorphism prevalence in the COX2 gene among patients with chronic polypoid rhinosinusitis and chronic rhinosinusitis and in the control group. American Journal of Medicine and Medical Sciences, 2024, 14 (12): 3149-3153. DOI 10.5923/j.ajmms.20241412.13 Tashkent Medical Academy, Tashkent, Uzbekistan.