Articles
| Open Access | IMMUNOPHENOTYPING OF BIOLOGICAL MATERIAL TO IDENTIFY HEMOBLASTOSIS MARKERS IN BLAST CRISIS FOR SELECTING ADEQUATE POLYCHEMOTHERAPY IN HEMOBLASTOSIS
Abdiev Kattabek Makhmatovich,Fayzullaeva Marjona Bakhodirovna,Abdikadirova Dilnura Rustambekovna,Akhmadova Rukhshona Zoirzhanovna , Samarkand State Medical UniversityAbstract
Hemoblastosis is a group of hematologic malignancies affecting the blood, bone marrow, and lymphatic system. The identification of specific markers during a blast crisis is critical for tailoring polychemotherapy regimens. Immunophenotyping, a powerful tool in the characterization of cellular populations, allows the identification of such markers, aiding in the classification of different hemoblastoses and the selection of optimal therapeutic approaches.
Keywords
Immunophenotyping, hemoblastosis, blast crisis, polychemotherapy, acute myeloid leukemia (aml), acute lymphoblastic leukemia (all), chronic myeloid leukemia (cml), flow cytometry, surface markers, biological material, leukemia classification, prognosis, treatment outcomes, bcr-abl, cd markers, personalized therapy, patient management, hematological malignancies, targeted therapy, biomarkers.
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