It is known that the interaction of diabetes and purulent infection with their simultaneous development leads to a complex and peculiar pathological process, causing a “syndrome of mutual burden" that requires a special comprehensive examination and treatment, deep understanding and adequate correction of changes occurring in the body. The mortality rate of patients with purulent diseases on the background of diabetes remains high and ranges from 6 to 44%, and it has been stable in recent years. Despite the successes achieved in the prevention and treatment of diabetic foot, 40-60% of all amputations of the lower extremities are still performed in patients with this pathology. 

gastrointestinal tract, endogenous intoxication index, colonies forming units, leukocyte intoxication index, medium-weight molecules, non-clostridial anaerobic infection.

Abdumazhidov A.S. The state of immunity in patients with purulent-inflammatory diseases of soft tissues on the background of diabetes mellitus // International Congress of Diabetologists of Central Asia. Collection of abstracts. Tashkent, 2006, p. 55.

Abikenova F.S. Hypoglycemic and antidiabetic properties of geraine // II-International Congress of Diabetologists of Central Asia. Collection of abstracts. Tashkent, 2006, p. 17.

Avdeeva T.V., Varshaevsky I.M., Shabanov I.Ya., Boklin A.A. Analysis of the results of surgical treatment of diabetic foot // Problems of endocrinology. -2010. - C. 6. - pp.13-16.

Agzamkhodzhaev S.M., Keinova I.E., Khusainov Yu.U. Magnetic therapy of purulent diseases in diabetes mellitus //Medical Journal of Uzbekistan. 2009. | N4.- pp. 32-34.

Agzamkhodzhaev S.M., Rakhmanov R.K., Yanbaeva T.A. Treatment of purulent wounds with adsorbents // Republican conference with international participation "Wounds and wound infection". Collection of abstracts. - Andijan. - 2008. - p. 34.

Adamyan A.A., Dobysh S.V., Kochergina L.D., Glossitsev S.P. Sorption and application therapy of the wounded in the conditions of medical care during disasters //International conference. "Disaster Medicine". Collection of abstracts. - Moscow. - 2003. - p. 155.

Adamyan A.A., Lizanets M.N., Dobysh S.V. and others. Laboratory results of powdered medical sorbents and prospects for their use in surgery //Bulletin of Surgery. -2002. - N 7-8. - pp. 37-41.

Adamyan A.A., Muradyan R.G., Kochergin L.D. Modern means of local wound treatment that stimulate reparative processes //Surgery. - 2004. - No. 1.-pp. 57-60.-184.

Adamyan A.A., Dobysh S.V., Glossev S.P. and others. Treatment of purulent wounds with gelatin and biologically active draining sorbents //Surgery. -2004. - No. 8.-pp. 28-31.

Azizov G.A., Yulchiev A.K., Jalilova F.M. Lymphatic therapy in the complex treatment of purulent-inflammatory complications of soft tissues in postthrombophlebitic syndrome //Republican conference with international participation "Wounds and wound infection". Collection of abstracts. - Andijan, 2008, pp. 30-11.

Akmatov B.A., Rafibekov D.S., Zholdoshbekov E.Zh., Shabdanaliev A.Sh. The use of sorption methods and laser irradiation in the combined treatment of purulent wounds in patients with diabetes mellitus // II -International Congress of Diabetologists of Central Asia. Collection of abstracts. Tashkent, 2006, p. 55.

Alekseev A. A., Buyanov V.M., RadzikhOAsky A.P., Shimanko I.I. Lymphogenic detoxification. - Kiev, Naukova dumka, 1988. - 232 p.

Aliev M.A., Popov T.A., Albazarov B.S. Application of sodium hypochlorite in purulent surgery //Republican conference with international participation "Wounds and wound infection". Collection of abstracts - Andijan - 2008.-p. 35.

Alimov A.T., Nurmukhammedov M.E., Babajanov A.B., Mukhammadiev D.D. Clinical and bacteriological analysis of purulent-septic diseases in diabetes mellitus //Republican conference with international participation "Wounds and wound infection". Collection of abstracts. - Andijan. - 2008. - p. 24.

Andreychik M.L., Gebesh V.V., Gnatyuk M.S. and others. Enterosorption: achievements, problems, prospects //Medical business. -2002. - N9. - pp. 12-19.

Ancipovich E.A., Molchanov V.F., Kadyshev Yu.G., Brusnitsina M.A. Selective intraarterial use of small doses of thienam and vasaprostan in the treatment of purulent foot diseases in patients with diabetes mellitus //Bulletin of Surgery. 2004. No. 1. pp. 76-78.

Antsiferov M.B. Complications of diabetes mellitus (clinic, diagnosis, treatment, prevention). - M., Medicine, 2008. - pp. 44-50.

Aripov U. A., Asamov R.E., Jamalov S.I. New perspectives in the treatment of diabetic foot // Scientific and practical conference “Modern aspects of diagnosis, treatment, and prevention of lower limb lesions in patients with diabetes mellitus.” Collection of abstracts. Moscow, 2006. pp. 15-17

Aripov U.A., Asamov R.E., Jamalov S.I., Imamov A.A. Transplantation of pancreatic islets in the complex treatment of diabetic foot syndrome //Surgery of Uzbekistan. - 2010. - No. 2. - pp. 22-25.

Asamov R.E., Jamalov S.I., Shukurov B.I. Modern tactics of treatment of patients with “diabetic foot”//International Conference "Surgery-2000". Collection of abstracts. - Moscow. - 2000. - pp. 487-48