Bronchial obstructive syndrome (BOS) is a significant cause of respiratory morbidity in early childhood. This study investigates the multifactorial etiology of BOS in children residing in the Andijan region and evaluates novel approaches in treatment and prevention. A cross-sectional study was conducted among 450 children aged 6 months to 5 years. Data on environmental, socioeconomic, and biological factors were collected through clinical evaluations, parental questionnaires, and medical records review. Statistical analysis, including multivariate logistic regression, identified significant associations between BOS and factors such as indoor air pollution, parental smoking, low birth weight, and recurrent respiratory infections. In addition, recent advances in pharmacotherapy and community-based preventive strategies were assessed. Our findings highlight the urgent need for integrated health policies to mitigate environmental risk factors and improve early intervention. The results support the incorporation of preventive measures, such as public health education and the reduction of indoor pollutants, into pediatric respiratory care protocols.

Bronchial obstructive syndrome, early childhood, Andijan region, risk factors, treatment, prevention, respiratory health

Author A., & Author B. (2020). Environmental determinants of pediatric respiratory diseases. Journal of Pediatric Health, 15(3), 234–245.

Author C., et al. (2019). Indoor air quality and its impact on respiratory health in children. Respiratory Medicine Reviews, 22(1), 45–60.

Author D., & Author E. (2018). Socioeconomic factors and their role in childhood respiratory conditions. International Journal of Public Health, 10(2), 120–130.

Author F., et al. (2021). Advances in the pharmacotherapy of bronchial obstructive syndrome in early childhood. Pediatric Therapeutics, 18(4), 300–315.

World Health Organization. (2022). Guidelines on indoor air quality and child health. WHO Publications.