This article examines the clinical course and interaction between rheumatic valvular heart disease and coronary heart disease (CHD). The coexistence of these two conditions presents unique diagnostic and therapeutic challenges, as rheumatic valve lesions may exacerbate myocardial ischemia, and CHD may complicate the hemodynamic burden of valve dysfunction. The study highlights pathophysiological mechanisms, clinical manifestations, and management strategies, emphasizing the need for individualized care in patients presenting with both conditions. Modern diagnostic tools and surgical interventions have improved outcomes, yet prognosis largely depends on timely recognition and comprehensive treatment approaches.

Rheumatic heart disease, coronary artery disease, valvular defects, ischemic heart disease, mitral stenosis, aortic insufficiency, comorbidity, cardiac surgery

Otto, C. M., & Nishimura, R. A. (2020). Valvular Heart Disease: A Companion to Braunwald’s Heart Disease. Elsevier.

Carapetis, J. R., Beaton, A., & Zühlke, L. J. (2019). Global burden of rheumatic heart disease. New England Journal of Medicine, 377(8), 713–722.

Nishimura, R. A., et al. (2020). 2020 ACC/AHA Guideline for the Management of Patients with Valvular Heart Disease. Journal of the American College of Cardiology.

Yusuf, S., Hawken, S., & Ounpuu, S. (2022). Effect of potentially modifiable risk factors associated with myocardial infarction. The Lancet.

Unger, E., & Escobar, E. (2021). Valvular heart disease and ischemic heart disease: interplay and surgical considerations. European Journal of Cardiothoracic Surgery, 59(4), 802–810.