The article investigates hazardous substances, their classification, and protective measures against their impact in chemical industry settings. The introduction highlights the health risks posed by chemical substances during production, noting their potential to contaminate workplace air, skin, and surfaces. According to GOST 12.1.007, hazardous substances are classified into four hazard classes based on an analysis of indicators such as maximum permissible concentration (MPC), median lethal dose (LD50), and inhalation poisoning probability coefficient (CVIO). The methods involve analyzing standards and toxicity metrics, as well as examining pathways of substance entry into the body (respiratory system, gastrointestinal tract, skin). The results show that acute poisoning occurs at high concentrations, while chronic poisoning develops from prolonged accumulation of substances like lead and mercury.

hazardous substances, toxicity, hazard classification, MPC, acute poisoning, chronic poisoning, chemical industry, occupational safety.

G.V. Makarov, A.Ya. Vasin, L.K. Marinina, P.I. Sofinsky and others. Labor protection in the chemical industry, Moscow, Khimiya, 1989, 496 p.; ill.

Voznesensky V.V., Zaitsev A.P. The latest respiratory and skin protection products, A textbook, Moscow, Military Knowledge LLP, 1999, 38c.; ill.

GOST 12.1.007. Harmful substances. Classification and general requirements

GOST 12.1.005. General sanitary and hygienic requirements for the air of the working area.

Yu.P. Pivovarov, V.V. Krolik, L.S. Zinevich Hygiene and the basics of human ecology, Rostov n/A : “Phoenix", 2002, - 512s.

N.F. Izmerov, A.A. Kasparov Occupational medicine. Introduction to the specialty, Moscow: “Medicine”, 2002, 392 p.

A.N. Pavlov, V.M. Kirilov Life safety and prospects for environmental development, Moscow : “Helios” 2002, 352 p.